Common Nausea, Vomiting, Decreased potassium level in blood, Fever, Chills, Decreased blood pressure, Increased creatine level in blood.

Expert advice for Ambisome Injection

Before you take amphotericin B, inform your doctor if you suffer from diabetes, liver/kidney problem or are on dialysis or have low potassium level in blood.
You should monitor your condition through regular laboratory evaluation of potassium, magnesium as well as renal, hepatic and hematopoietic function.
Take precautions as amphotericin B may reduce the ability to drive or operate machinery.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Q. Is Ambisome fungistatic or fungicidal?
Ambisome is fungicidal in nature, it acts by killing the fungus

Q. Is Ambisome light sensitive?
Ambisome is not light sensitive

Q. What is Ambisome liposomal?
Liposomal Ambisome is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Ambisome can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Ambisome an antibiotic?
Yes, Ambisome is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q. Is Ambisome testing dose needed?
Yes, administration of Ambisome is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q. How is Ambisome administered?
Ambisome is either administered as intravenous injection or infusion by a registered medical professional only

Q. How does Ambisome cause nephrotoxicity and hyperkalemia?
Ambisome can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.