USED FOR:
Serious fungal Infections
Kala-azar
COMPOSITION:
Amphotericin B (50mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
Amphonex 50mg Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Amphonex 50mg Injection is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Amphonex 50mg Injection may cause side effects which could affect your ability to drive.
Amphonex 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amphonex 50mg Injection is recommended.However, inform your doctor if you have any underlying kidney disease.
There is limited information available on the use of Amphonex 50mg Injection in patients with liver disease. Please consult your doctor.
Uses of Amphonex Injection
Amphonex 50mg Injection is used in the treatment of serious fungal infections and kala-azar.
How to use Amphonex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Amphonex Injection works
Amphonex 50mg Injection is an antifungal medicine. It kills fungus by destroying the fungal cell membrane.
Common Nausea, Vomiting, Decreased potassium level in blood, Fever, Chills, Decreased blood pressure, Increased creatine level in blood.
Expert advice for Amphonex Injection
Before you take amphotericin B, inform your doctor if you suffer from diabetes, liver/kidney problem or are on dialysis or have low potassium level in blood.
You should monitor your condition through regular laboratory evaluation of potassium, magnesium as well as renal, hepatic and hematopoietic function.
Take precautions as amphotericin B may reduce the ability to drive or operate machinery.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Q. Is Amphonex fungistatic or fungicidal?
Amphonex is fungicidal in nature, it acts by killing the fungus
Q. Is Amphonex light sensitive?
Amphonex is not light sensitive
Q. What is Amphonex liposomal?
Liposomal Amphonex is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphonex can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphonex an antibiotic?
Yes, Amphonex is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphonex testing dose needed?
Yes, administration of Amphonex is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphonex administered?
Amphonex is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphonex cause nephrotoxicity and hyperkalemia?
Amphonex can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
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