Coaprovel 300mg/12.5mg Tablet 
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NOTICE: unsafe with : Alcohol
USED FOR:
High blood pressure
COMPOSITION:
Irbesartan (300mg) + Hydrochlorothiazide (12.5mg)
Therapeutic Uses:
cardiac
CAUTION
Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
WEIGH RISKS VS BENEFITS
Coaprovel 300mg/12.5mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Coaprovel 300mg/12.5mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Coaprovel 300mg/12.5mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Coaprovel 300mg/12.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Coaprovel 300mg/12.5mg Tablet may be needed. Please consult your doctor.Use of Coaprovel 300mg/12.5mg Tablet is not recommended in patients with severe kidney disease.
CAUTION
Coaprovel 300mg/12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Coaprovel 300mg/12.5mg Tablet may be needed. Please consult your doctor.
Uses of Coaprovel Tablet
Coaprovel 300mg/12.5mg Tablet is used in the treatment of high blood pressure.
How to use Coaprovel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coaprovel 300mg/12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Coaprovel 300mg/12.5mg Tablet works
Coaprovel 300mg/12.5mg Tablet is a combination of two medicines: Irbesartan and hydrochlorothiazide which lower blood pressure effectively. Irbesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Common Nausea, Altered taste, Stomach upset, Diarrhoea, Weakness, Dizziness, Headache, Glucose intolerance, Increased blood uric acid, Increased blood lipid level, Electrolyte imbalance, Decreased blood pressure.
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