Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.

Palio D Capsule SR may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Palio D Capsule SR should be used with caution during lactation. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Palio D Capsule SR may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.

Palio D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Palio D Capsule SR may be needed. Please consult your doctor.

Palio D Capsule SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Palio D Capsule SR may not be needed in these patients. Please consult your doctor.