Common Nausea, Vomiting, Mouth ulcer, Anemia, Decreased blood cells (red cells, white cells, and platelets), Bone-marrow suppression, Decreased white blood cell count, Diarrhoea, Decreased white blood cell count (neutrophils).

Expert advice for Clokeran Tablet

Do not receive live vaccine (such as measles, mumps, rubella and others) while using chlorambucil, and avoid contact with anyone who has recently received a live vaccine as there are chances that the virus could be passed on to you.
You may be regularly monitored for blood count while taking chlorambucil.
Do not take chlorambucil if you have recently undergone radiotherapy or received other cytotoxic agents.
Caution has to be followed if you have a liver or kidney problems. 
Regular monitoring is required if your child is having nephrotic syndrome; or if you have been prescribed high pulse dosing regimens and have a history of seizure disorder.
Do not take chlorambucil if you have rare hereditary problems of glucose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medication.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Q. How is Clokeran administered?
Clokeran is administered orally in tablet form

Q. Why is Clokeran toxic to cancer cells/ how does Clokeran work?
Clokeran belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth

Q. Does Clokeran cause hair loss/constipation?
No, hair loss or constipation has not been reported with the use of Clokeran.

Q. What is Clokeran used for?
Clokeran is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood)

Q. How is Clokeran excreted?
Clokeran is metabolized in liver to form nontoxic compounds which are excreted in urine

Q. Does Clokeran need to be refrigerated?
Clokeran has to be stored in a refrigerator at 2 °C – 8 °C