Related Warnings
Alcohol

No interaction found

WEIGH RISKS VS BENEFITS
Pregnancy
WEIGH RISKS VS BENEFITS

Histo Calamine Lotion may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation

No information is available on the use of Histo Calamine Lotion during lactation. Please consult your doctor.

Driving

It is not known whether Histo Calamine Lotion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

Histo Calamine Lotion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Histo Calamine Lotion may not be needed in these patients. Please consult your doctor.

Liver

Histo Calamine Lotion is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Histo Calamine Lotion may not be needed in these patients. Please consult your doctor.


Aloe Vera   5% w/v

Uses of Aloe Vera
Aloe Vera is used in the treatment of pain.

How to use Aloe Vera
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Histo Calamine Lotion works
Healing properties: Glucomannan, a mannose-rich polysaccharide, and gibberellin, a growth hormone, interacts with growth factor receptors on the fibroblast, thereby stimulating its activity and proliferation, which in turn significantly increases collagen synthesis after topical and oral Aloe vera. Aloe gel not only increased collagen content of the wound but also changed collagen composition (more type III) and increased the degree of collagen cross linking. Due to this, it accelerated wound contraction and increased the breaking strength of resulting scar tissue.Effects on skin exposure to UV and gamma radiation: The administration of aloe vera gel, an antioxidant protein, metallothionein, is generated in the skin, which scavenges hydroxyl radicals and prevents suppression of superoxide dismutase and glutathione peroxidase in the skin. It reduces the production and release of skin keratinocyte-derived immunosuppressive cytokines such as interleukin-10 (IL-10) and hence prevents UV-induced suppression of delayed type hypersensitivity.Anti-inflammatory action: Aloe vera inhibits the cyclooxygenase pathway and reduces prostaglandin E2 production from arachidonic acid. Effects on the immune system: Alprogen inhibit calcium influx into mast cells, thereby inhibiting the antigen-antibody-mediated release of histamine and leukotriene from mast cells.Antiviral and antitumor activity: These actions may be due to indirect or direct effects. Indirect effect is due to stimulation of the immune system and direct effect is due to anthraquinones. The anthraquinone aloin inactivates various enveloped viruses such as herpes simplex, varicella zoster and influenza.Moisturizing and anti-aging effect: Mucopolysaccharides help in binding moisture into the skin. Aloe stimulates fibroblast which produces the collagen and elastin fibers making the skin more elastic and less wrinkled. It also has cohesive effects on the superficial flaking epidermal cells by sticking them together, which softens the skin. The amino acids also soften hardened skin cells and zinc acts as an astringent to tighten pores. It also has anti-acne effect.Antiseptic effect: Aloe vera contains 6 antiseptic agents: Lupeol, salicylic acid, urea nitrogen, cinnamonic acid, phenols and sulfur. They all have inhibitory action on fungi, bacteria and viruses.

Side Effects:

Common Cramps, Electrolyte imbalance, Diarrhoea, Colon staining, Laxative effect, Skin irritation.

Calamine   8% w/v

Uses of Calamine
Calamine is used in the treatment of dermatitis, itching and eczema.

How to use Calamine
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Histo Calamine Lotion works
Calamine has mild astringent and antipruritic actions. Calamine is an anti-itch medication that works by causing a cooling sensation as it evaporates on your skin.

Side Effects:

Common Rash, Mouth swelling, Vomiting, Gastritis, Urticaria, Hypersensitivity reaction, Itching, Skin irritation, Chest tightness, Shortness of breath.

Camphor   0.1% w/v

Uses of Camphor
Camphor is used in the treatment of dermatitis, itching and eczema.

How to use Camphor
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Histo Calamine Lotion works
Camphor belongs to the class of medicines called rubefacients/antitussives. When applied to the skin, it increases blood flow and local temperature of the affected area which suppresses and temporarily relieves pain sensations. It also eases cough, nasal/throat irritation by moistening air passages when used along with steam.

Side Effects:

Common Skin irritation, Hypersensitivity reaction, Irritation of ear, Allergic skin rash.

Expert advice for Camphor

Do not apply this medicine on wound/damaged skin, eyes and nose.
Tell your doctor if you have sensitive skin. Avoid exposure to sunlight as it can cause photosensitivity.
Do not administer camphor based medicines orally in large amounts as it can be toxic.
Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
Do not take if allergic to camphor or any of its ingredients.
Do not take if below 2 years.

Frequently Asked Questions

Q. Is Camphor edible?
Edible Camphor is different from the chemically made Camphor. Camphor used in cooking is ‘edible Camphor'

Q. Is Camphor poisonous?
Yes, if Camphor is applied to broken skin, it can enter the body quickly and reach concentrations that are high enough to cause poisoning. Overdose of Camphor can result in poisoning.

Q. Is Camphor saturated or unsaturated?
Camphor is unsaturated

Q. Is camphor soluble in water?
No, camphor is not soluble in water.

Q. Is Camphor and naphthalene same?
No, Camphor and naphthalene are not same.

Q. Does Camphor cause cancer?
There is no scientific information available which confirms that Camphor causes cancer.

Q. Does Camphor burn with a flame?
Yes, Camphor releases hydrocarbon gases that will burn and releases flame.

Diphenhydramine Topical   1% w/v

Uses of Diphenhydramine Topical
Diphenhydramine Topical is used in the treatment of allergic disorders.

How to use Diphenhydramine Topical
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Histo Calamine Lotion works
Diphenhydramine Topical is an antihistaminic medication. It blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions.

Expert advice for Diphenhydramine Topical
Avoid driving or operating dangerous machinery as it may decrease alertness. Avoid consuming alcohol when taking the Diphenhydramine Topical, as it may cause excessive sleepiness or drowsiness.

Frequently Asked Questions

Q. Is diphenhydramine topical a blood thinner/narcotic/water soluble?
No, it is an antihistaminic drug and not a blood thinner or narcotic

Q. Is diphenhydramine hydrochloride safe?
It is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Glycerin   6.25% w/v

Uses of Glycerin
Glycerin is used in constipation.

How to use Glycerin
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Histo Calamine Lotion works
Glycerin works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Side Effects:

Common Dehydration.

Expert advice for Glycerin
Avoid taking a Glycerin for more than 1 week, unless prescribed by the doctor, as it leads to dependency on the laxative action to produce a bowel movement.  Together with Glycerin, fiber rich diet containing whole grain bread and cereals, bran, fruits and green leafy vegetables, is essential to maintain healthy bowel function. A Glycerin should preferably be taken at bedtime because it requires 6 to 8 hours to show impact. Notify your doctor if you are on a low-sugar diet because the Glycerin contains sugars. Take Glycerin after 2 hours from other medicines, as it may interfere with the absorption of other medicines.

Available Substitutes
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