Ketriplin Cream 
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USED FOR:
Depression
General Anaesthesia
Neuropathic pain
COMPOSITION:
Amitriptyline (40mg)
Ketamine (20mg)
Therapeutic Uses:
neuro cns
pain analgesics
No interaction found
WEIGH RISKS VS BENEFITS
Ketriplin Cream may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
CAUTION
Ketriplin Cream is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well.Ketriplin Cream may impair your alertness which may affect your ability to drive.
Ketriplin Cream is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ketriplin Cream may not be needed in these patients. Please consult your doctor.
CAUTION
Ketriplin Cream should be used with caution in patients with liver disease. Dose adjustment of Ketriplin Cream may be needed. Please consult your doctor.
Uses of Amitriptyline
Amitriptyline is used in the treatment of depression and neuropathic pain.It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
How to use Amitriptyline
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Ketriplin Cream works
Amitriptyline increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Common Sleepiness, Blurred vision, Increased heart rate, Dryness in mouth, Constipation, Weight gain, Difficulty in urination, Orthostatic hypotension (sudden lowering of blood pressure on standing).
Expert advice for Amitriptyline
The main dose should be taken at night as this drug may produce drowsiness or sleepiness. It can take 4 to 6 weeks for Amitriptyline to start working. You should continue the treatment for at least 6 months after you feel better to stop depression from coming back. If your doctor asks you to stop Amitriptyline, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Avoid driving or operating machinery as it may decrease alertness. Avoid consuming alcohol when taking the Amitriptyline, as it may cause excessive drowsiness and calmness. The addiction/dependence potential of Amitriptyline is very less. It may be extremely dangerous in overdose.
Q. Is Amitriptyline safe?
Amitriptyline is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Amitriptyline a steroid?
No, Amitriptyline is not a steroid. It belongs to class of medication called as tricyclic antidepressant.
Q. Can I take Amitriptyline with Betahistine?
Amitriptyline has not been clinically studied when used along with Betahistine. So there are no reports of any drug-drug interactions or harmful effects when these are used together.
Uses of Ketamine
Ketamine is used for general Anaesthesia.
How to use Ketamine
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Ketriplin Cream works
Ketamine causes a reversible loss of consciousness allowing surgery without pain and distress.
Common Nausea, Agitation, Double vision, Erythema, Vomiting, Nightmare, Abnormal dreams, Abnormal behavior, Hallucination, Generalized tonic-clonic seizure, Increased respiratory rate , Hypertonia, Increased blood pressure, Tachycardia, Confusion, Nystagmus (involuntary eye movement).
Expert advice for Ketamine
Do not eat or drink for at least six hours before administration of ketamine.Â
Inform your doctor if you have history of alcoholism, drug abuse or addiction, mental health problem, glaucoma (increased pressure in eye), porphyria (inherited disease that affects the blood), fits.Â
Ketamine should usually be combined with a painkiller when used for an operation on the chest or abdominal organs.Â
Do not drink alcohol at least for 24 hours after surgical procedure, as it may worsen the side effects.
Do not drive or operate machines at least 24 hours after surgical procedure, as ketamine may make you feel dizzy or sleepy.
Avoid if Patients is allergic to ketamine or any of its ingredients.
Do not take if Patients is suffering from severe heart disease, who have recently suffered a stroke or serious head or brain injury
Avoid if Pregnant and lactating women.
Q. Is Ketamine addictive?
Ketamine addiction can occur if the drug is taken multiple times and may develop either a mental or physical dependence on the drug effects
Q. Is Ketamine an opiate/ narcotic/ stimulant/ controlled substance/ barbiturate?
No. Ketamine is a general anaesthetic and a controlled substance. It is not an opiate, barbiturate narcotic or stimulant
Q. Is Ketamine safe?
Ketamine is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Ketamine dangerous?
Ketamine is dangerous if taken at high doses
Q. Does Ketamine make you lose weight?
Yes. Ketamine can cause loss of appetite and weight loss.
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