Carpine 0.5% Injection 
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USED FOR:
Dry mouth after radiotherapy of head and neck cancer
COMPOSITION:
Pilocarpine (0.5%)
Therapeutic Uses:
ophthal
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Carpine 0.5% Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
SAFE
Carpine 0.5% Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Carpine 0.5% Injection may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
CAUTION
Carpine 0.5% Injection should be used with caution in patients with kidney disease. Dose adjustment of Carpine 0.5% Injection may be needed. Please consult your doctor.
CAUTION
Carpine 0.5% Injection should be used with caution in patients with liver disease. Dose adjustment of Carpine 0.5% Injection may be needed. Please consult your doctor.Use of Carpine 0.5% Injection is not recommended in patients with severe liver disease.
Uses of Carpine Injection
Carpine 0.5% Injection is used in the treatment of dry mouth after radiotherapy of head and neck cancer.
How to use Carpine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Carpine Injection works
Carpine 0.5% Injection works by increasing the secretion of saliva in the mouth.
Common Headache, Sweating, Frequent urge to urinate, Flu-like symptoms.
Expert advice for Carpine Injection
Inform your doctor if you have eye inflammation, suffer from asthma, liver, kidney or heart diseases, Parkinson’s disease, stomach ulcer, have problems in passing urine, high blood pressure, narrow angle glaucoma (increased eyeball pressure due to obstruction to the outflow of fluid).
Drink sufficient water to reduce dehydration due to excessive sweating caused by pilocarpine.
The back layer of your eye (fundus) may be examined before starting pilocarpine therapy.
You may be regularly monitored for visual fields and intra-ocular pressure on long term therapy with pilocarpine for glaucoma.
Do not drive or operate machinery as pilocarpine causes dizziness and blurring of vision especially in the night.
Tell your doctor if you are pregnant, planning to become pregnant or are breast-feeding.
Q. Does Carpine increase or decrease heart rate?
Carpine can decrease the heart rate. However, it does not increase the heart rate
Q. Does Carpine cause weight gain/increase blood pressure?
Carpine increases blood pressure. However, no clinically relevant effect on weight has been reported with the use of Carpine
Q. Does Carpine help dry eyes?
Yes, Carpine helps dry eyes by increasing the production of tears
Q. Does Carpine work?
Carpine acts by increasing the activity of chemical acetylcholine, thereby, increasing the secretion from various glands including salivary glands and tear glands. Due to its cholinergic effect, it also constricts the pupil of the eye and improves the outflow of aqueous humor (fluid in within the eye) contributing to reduction in eyeball pressure
Q. Does Carpine cause blurred vision/hair loss?
Yes, Carpine causes blurred vision. But it does not cause hair loss
Q. How does Carpine affect heart rate?
Carpine decreases heart rate by increasing the effect of a chemical called as acetylcholine
Q. How does Carpine lower intraocular pressure?
Carpine lowers intraocular pressure by constricting the ciliary muscle of the eyes, therefore increasing the outflow of fluid (aqueous humor) from posterior part of the eye.
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