Interaction with alcohol is unknown. Please consult your doctor.

Comvac 4 HB Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Comvac 4 HB Injection should be used with caution during lactation. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

It is not known whether Comvac 4 HB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Comvac 4 HB Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Comvac 4 HB Injection may not be needed in these patients. Please consult your doctor.

Comvac 4 HB Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Comvac 4 HB Injection may not be needed in these patients. Please consult your doctor.