USED FOR:
HIV infection
Chronic hepatitis B virus (HBV) infection
COMPOSITION:
Lamivudine (150mg)
Zidovudine (300mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
Duovir EP 150 mg/300 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Duovir EP 150 mg/300 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Duovir EP 150 mg/300 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Duovir EP 150 mg/300 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Duovir EP 150 mg/300 mg Tablet may be needed. Please consult your doctor.
Duovir EP 150 mg/300 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Duovir EP 150 mg/300 mg Tablet may be needed. Please consult your doctor.Use of Duovir EP 150 mg/300 mg Tablet is not recommended in patients with moderate to severe liver disease.
Uses of Lamivudine
Lamivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.
How to use Lamivudine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duovir EP 150 mg/300 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Duovir EP 150 mg/300 mg Tablet works
Lamivudine prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.
Common Fatigue, Headache, Nausea, Vomiting, Abdominal pain, Dizziness, Ear infection, Nasal infection, Throat infection, Sore throat, Skin rash, Muscle pain, Fever, Chills, Diarrhoea.
Expert advice for Lamivudine
Consult your doctor if you have diabetes and are using insulin.
Patients receiving this therapy are always at a risk for infections and hence should report any such cases to the doctor.
Consult your doctor if you take any prescription medication; Inform your doctor if you take other medicine for treatment of HIV or hepatitis B infection, hairy cell leukemia [a type of blood cancer], or antibiotics for infection.
Lamivudine may rarely cause a serious side effect like lactic acidosis with symptoms such as pain or weakness of muscle, numbness or feeling cold in arms or legs, stomach pain, nausea, vomiting, lack of breath, aberrant heart rate, dizziness, weak or tired feeling; hence, inform the doctor immediately if you experience any of these symptoms.
It is possible to pass on HIV when on this medication and hence it is important to take necessary precautions to prevent HIV from spreading.
Inform you doctor if you notice signs of change in the distribution of fat (lipodystrophy), erosion of bones (osteronecrosis), or inflammation of pancreas (pancreatitis).
If you are on therapy it is important to use effective non hormonal method of contraception or condom so that a pregnancy can be avoided.
Use with caution in pediatric patients with a history of pancreatitis or other significant risk factors for pancreatitis.
Q. Can lamivudine cure hepatitis B?
Lamivudine is used to treat hepatitis B but some patients may be resistant to this dru
Q. Can Lamivudine be crushed?
Lamivudine cannot be crushed but it can be broken into two parts to give it to children. Please go by the recommendation of the doctor
Q. Can Lamivudine cause anemia?
Lamivudine may cause anemia as a side effect in some patients. Kindly consult your doctor in case any side effects are observed.
Uses of Zidovudine
Zidovudine is used in the treatment of HIV infection.
How to use Zidovudine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duovir EP 150 mg/300 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Duovir EP 150 mg/300 mg Tablet works
Zidovudine prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.
Common Fatigue, Headache, Decreased appetite, Nausea, Vomiting, Muscle pain.
Expert advice for Zidovudine
Inform you doctor if you have or ever had any liver problems or liver disease including hepatitis B or C or kidney problems.
Inform your doctor if you are suffering from diabetes or are overweight and on insulin therapy.
As treatment with zidovudine does not reduce the risk of passing HIV on to others by sexual contact or blood transfer, discuss with your doctor about necessary precautions (practicing safer sex and making other life-style changes) to be taken to avoid spreading of HIV virus to others.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Q. Is Zidovudine an antibiotic?
No, Zidovudine is not an antibiotic; it belongs to a class of drugs called antiretrovirals
Q. Is Zidovudine a prodrug?
Yes, Zidovudine is a prodrug and must be activated (by phosphorylation in lymphocytes) in the body to exert its antiviral action
Q. Is zidovudine a protease inhibitor?
No, zidovudine is not a protease inhibitor; it is a nucleoside analogue reverse transcriptase inhibitor
Q. How does Zidovudine work?
Zidovudine belongs to a group of medications called nucleoside analogue reverse transcriptase inhibitors (NRTIs), also known as antiretrovirals. Zidovudine does not cure HIV infection; it reduces the amount of viruses in the body by inhibiting the chemical (viral reverse transcriptase) which is essential for the virus to grow. Further, Zidovudine also increases some white blood cells (CD4 cells) of the body that are important in fighting infections.
Q. What is Zidovudine used for?
Zidovudine is used in combination with other antiretroviral medicines for the treatment of human immunodeficiency virus (HIV) infection
Q. How is Zidovudine administered?
Zidovudine can be administered as tablets, syrups and suspension in combination with other antiretroviral medications
Q. Does Zidovudine cause muscle pain?
Yes, muscle pain is a known adverse effect of use Zidovudine
Q. Does Zidovudine cause lipodystrophy?
There are no known effects of Zidovudine on lipid distribution and it is not known to cause lipodystrophy
Q. How does Zidovudine cause anemia?
Zidovudine is known to cause bone marrow depression and thereby cause anemia (reduction in red blood cell count)
Q. How much does Zidovudine cost?
The price of Zidovudine may vary depending upon the brand prescribed to you.Please read the instruction on the package for the correct price of the product.
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