Pause D 500 mg/50 mg Tablet 
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NOTICE: unsafe with : Alcohol
COMPOSITION:
Tranexamic Acid (500mg)
Diclofenac (50mg)
Therapeutic Uses:
blood related
ophthal
CAUTION
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Pause D 500 mg/50 mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Pause D 500 mg/50 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Do not drive unless you are feeling well.Pause D 500 mg/50 mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.
CAUTION
Pause D 500 mg/50 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pause D 500 mg/50 mg Tablet may be needed. Please consult your doctor.
Pause D 500 mg/50 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pause D 500 mg/50 mg Tablet may not be needed in these patients. Please consult your doctor.
Uses of Tranexamic Acid
Tranexamic Acid is used in the treatment of bleedingIt is used to prevent or reduce bleeding for short period of time in conditions like heavy periods, dysfunctional uterine bleeding, nosebleed, tooth removal, after prostate surgery or after bladder surgery.
How to use Tranexamic Acid
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pause D 500 mg/50 mg Tablet is to be taken with food.
How Pause D 500 mg/50 mg Tablet works
Tranexamic Acid prevents the breakdown of clots and stops bleeding.
Common Nausea, Vomiting, Diarrhoea.
Expert advice for Tranexamic Acid
Do not take tranexamic acid:
before the start of menstruation.
If you are a woman >45 years of ageÂ
If you are allergic to tranexamic acid or any of the ingredients of this medicine
Do not continue tranexamic acid and consult your doctor If you experience skin rashes or other serious symptoms like swelling of face, lips and throat causing breathlessness or difficulty swallowing, as this may denote allergy.Â
Consult your  doctor if menstrual bleeding is not reduced after three menstrual cycles.
To be sure this medication is not causing harmful effects, your vision may need to be tested while you are using tranexamic acid. Follow your doctor's instructions.
Q. What is Tranexamic Acid?
Tranexamic Acid belongs to a group of medicines called anti-fibrinolytics, used to control bleeding. When you bleed, your body form clots to stop the bleeding. In some people these clots break down causing too much bleeding. Tranexamic Acid stops these clots from dissolving, hence reduces bleeding.
Q. Is Tranexamic Acid an over the counter product?
No, Tranexamic Acid is not an over the counter product. it is available as a prescription medicine only.
Q. How long can I take Tranexamic Acid?
It is advisable to take Tranexamic Acid, only for a duration as advised by your doctor.
Q. Does Tranexamic Acid stop menstruation (periods)?
Tranexamic Acid helps to reduce excessive bleeding during a heavy menstrual cycle in women with regular cycles (25-31 days) with not more than 3 days individual variability in cycle duration.
Q. Does Tranexamic Acid affect ovulation?
No, Tranexamic Acid is not known to affect ovulation.
Q. Is Tranexamic Acid safe?
Yes, Tranexamic Acid is safe if used for prescribed duration in prescribed doses as advised by your doctor.
Q. Is Tranexamic Acid an anticoagulant?
No, Tranexamic Acid is not an anticoagulant. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid an non-steroidal antiinflammatory drug (NSAID) or a pain killer?
No, Tranexamic Acid is not a non-steroidal antiinflammatory drug (NSAID) or a pain killer.
Q. Is Tranexamic Acid a hormone?
No, Tranexamic Acid is not a hormone. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid a contraceptive?
No, Tranexamic Acid is not a contraceptive. It belongs to a group of medicines called anti-fibrinolytics
Q. Is Tranexamic Acid a blood thinner?
No, Tranexamic Acid is not a blood thinner. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid a steroid?
No, Tranexamic Acid is not a steroid. It belongs to a group of medicines called anti-fibrinolytics.
Q. Does Tranexamic Acid help in relieving cramps (period pain)?
No, Tranexamic Acid does not help in relieving menstrual cramps (period pain).
Q. Does Tranexamic Acid increases your blood pressure?
There are no reports of Tranexamic Acid causing an increase in blood pressure. Please consult your doctor in case you experience this symptom while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid cause weight gain?
Weight gain has not been reported as a side effect of Tranexamic Acid. Please consult your doctor if you experience excessive weight gain while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid affect fertility?
No, Tranexamic Acid is not known to affect fertility. Please talk to your doctor if you are planning to become pregnant and you are taking Tranexamic Acid.
Q. Does Tranexamic Acid make you tired?
Tiredness has not been reported as a side effect of Tranexamic Acid. Please talk to your doctor in case you experience excessive tiredness while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid prolonged periods?
No, Tranexamic Acid is not known to prolong periods. Please consult your doctor in case you experience this side effect while you are taking Tranexamic Acid.
Q. Can I take Tranexamic Acid with an intrauterine device (IUD) like copper-T?
Tranexamic Acid has been used to treat heavy or prolonged bleeding when an intrauterine device (IUD) like copper-T was in place but the safety of using Tranexamic Acid in this situation has not been established. Please consult your doctor before using Tranexamic Acid while you have an intrauterine device like copper-T in place.
Q. Can I take Tranexamic Acid with ibuprofen?
Tranexamic Acid can be taken with ibuprofen as there are no interactions reported between the two medicines. However, interactions between the two can occur. Please talk to your doctor if you have to take the two medicines together.
Q. Can I take Tranexamic Acid with the oral contraceptives (pills)?
There have been reports suggesting that either Tranexamic Acid or oral contraceptives (pills) containing ethinylestradiol can increase the toxicity of the other by increasing the risk of clot formation in your blood vessels leading to complications like a heart attack. Please consult your doctor in case you are taking these medicines together.
Q. Can I take Tranexamic Acid with amoxicillin?
No interactions have been reported between Tranexamic Acid and amoxicillin. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with a combination of paracetamol and codeine?
No interactions have been clinically observed while taking Tranexamic Acid and a combination of paracetamol with codeine. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with oral contraceptives containing only progesterone like mini pill and medroxyprogesterone acetate?
Tranexamic Acid can be taken with oral contraceptives containing only prgesterone as there are no drug interactions reported. However this does not role out the possibilty of interactions existing. Please talk to your doctor before taking Tranexamic Acid if you are already taking a progesterone containing oral contraceptive like mini-pill and medroxyprogesterone acetate.
Q. Can I take Tranexamic Acid with paracetamol?
No interactions have been reported between Tranexamic Acid and paracetamol. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with mefenamic acid?
No interactions have been reported between Tranexamic Acid and mefenamic acid. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with diclofenac?
No drug interaction of Tranexamic Acid with diclofenac has been clinically observed. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Uses of Diclofenac
Diclofenac is used in fever, headache, arthralgia, muscle pain, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
How to use Diclofenac
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pause D 500 mg/50 mg Tablet is to be taken with food.
How Pause D 500 mg/50 mg Tablet works
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (redness and swelling), fever and pain.
Common Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.
Expert advice for Diclofenac
It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Diclofenac can raise a risk of blood clots, heart attack, or a stroke. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Q. Can Diclofenac be used along with warfarin?
No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.
Q. Is Diclofenac a painkiller?
Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.
Q. Is Diclofenac a narcotic?
No, Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
Q. Can I use Diclofenac along with vitamins?
Yes, Diclofenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can Diclofenac be used for the treatment of hepatitis?
No, Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.
Q. Can Diclofenac be used after C-section?
Yes, Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.
Q. Can I take Diclofenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).
Q. Can I take Diclofenac while I am on thyroxine?
Yes, Diclofenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Why Diclofenac should be stopped before surgery?
Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.
Q. What are the contraindications for Diclofenac?
Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.
Q. Can Diclofenac affect the chance of conceiving?
Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Why does Diclofenac cause an ulcer?
Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.
Q. Why is Diclofenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Is Diclofenac good for back pain?
Yes, Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.
Q. Can I use Diclofenac during my fever treatment?
Yes, Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.
Q. Can I use Diclofenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.
Q. Can I use Diclofenac to treat urinary tract infections (UTI)?
Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.
Q. Can Diclofenac cause sedation?
Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.
Q. Can I take Diclofenac for kidney stones?
Yes,Diclofenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.
Q. Can I use Diclofenac for the treatment of arthritis?
Yes, Diclofenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .
Q. Can I use Diclofenac with diuretics?
No, Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can I use Diclofenac with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Diclofenac. Mifepristone is used for medical abortion.
Q. Can I use Diclofenac with lithium?
No.These drugs should not be used together as Diclofenac increases the blood levels of lithium which may further increase the side effects.
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