Depranil Plus 5 mg/25 mg Tablet 
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NOTICE: unsafe with : Alcohol
USED FOR:
Short term anxiety
Depression
Epilepsy
COMPOSITION:
Diazepam (5mg)
Imipramine (25mg)
Therapeutic Uses:
neuro cns
CAUTION
Depranil Plus 5 mg/25 mg Tablet may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Depranil Plus 5 mg/25 mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
CAUTION
Depranil Plus 5 mg/25 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well.As Depranil Plus 5 mg/25 mg Tablet may impair your alertness or cause drowsiness or blurred vision, and this may affect your ability to drive.
CAUTION
Depranil Plus 5 mg/25 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Depranil Plus 5 mg/25 mg Tablet may be needed. Please consult your doctor.
CAUTION
Depranil Plus 5 mg/25 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Depranil Plus 5 mg/25 mg Tablet may be needed. Please consult your doctor.Regular monitoring of liver function tests is recommended while you are taking this medicine.
Uses of Diazepam
Diazepam is used in the treatment of short term anxiety, epilepsy, muscle spasms and alcohol withdrawal.
How to use Diazepam
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depranil Plus 5 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Depranil Plus 5 mg/25 mg Tablet works
Diazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Common Sleepiness, Memory impairment, Uncoordinated body movements, Dizziness, Headache, Dryness in mouth, Fatigue, Depression, Irritability, Slurred speech, Constipation.
Expert advice for Diazepam
If you are taking Diazepam for the treatment of insomnia and anxiety, it should not be used more than 4 weeks. It may become less effective over the time. It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery. Avoid consuming alcohol when taking the Diazepam, as it may cause excessive sleepiness or drowsiness. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems. The addiction / habit-forming potential of Diazepam is very high.
Q. Is Diazepam an opioid/ painkiller/ barbiturate/ sedative/ muscle relaxant?
Diazepam belongs to a class of medication called as benzodiazepine. It produces sedation and also causes muscle relaxation. It is not a barbiturate, and does not relieve pain
Q. Is Diazepam a sleeping pill?
Diazepam is used as sedative drug which induces sleep
Q. Is Diazepam a narcotic/controlled drug?
Diazepam is considered as a narcotic drug, as it has low, but definite potential to cause addiction, resulting in abuse of the drug; hence, its sale is controlled. It is available only according to the prescription of a doctor
Q. How long can I take Diazepam for?
It is advisable to take this drug only till prescribed by the doctor
Q. Can I take Diazepam for back pain/toothache/anxiety/hangover?
Diazepam is used in the treatment of short-term relief (2-4 weeks) of severe anxiety. It is not a pain-relieving medication, and cannot be used to relieve pain. It does not relieve hangover
Q. Does Diazepam help with opioid withdrawal?
Diazepam is used to induce sleep, control fits and other symptoms of withdrawal of opioids as well as other depressant drugs
Q. Does Diazepam cause weight gain/drowsiness/thins blood?
Drowsiness is the most common side effect of Diazepam. There is no evidence that it causes weight gain, or thinning of blood
Q. Does Diazepam show on blood test?
Yes, Diazepam can be detected in blood, as well as urine, even when it is taken at prescribed doses
Q. Does Diazepam make you high?
Diazepam is a benzodiazepine, which calms down the brain to relieve symptoms of brain hyperactivity. This effect may be perceived by some as pleasant, or ‘getting high'. Diazepam is considered as a narcotic drug, as it has low, but definite potential to cause addiction, resulting in abuse of the drug; hence, its sale is controlled. It is available only according to the prescription of a doctor.
Uses of Imipramine
Imipramine is used in the treatment of depression and bed-wetting.It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
How to use Imipramine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depranil Plus 5 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Depranil Plus 5 mg/25 mg Tablet works
Imipramine increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Common Sleepiness, Blurred vision, Constipation, Weight gain, Dryness in mouth, Difficulty in urination, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing).
Expert advice for Imipramine
The main dose should be taken at night as this drug may produce drowsiness or sleepiness. It can take 4 to 6 weeks for Imipramine to start working. You should continue the treatment for at least 6 months after you feel better to stop depression from coming back. If your doctor asks you to stop Imipramine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Avoid driving or operating machinery as it may decrease alertness. Avoid consuming alcohol when taking the Imipramine, as it may cause excessive drowsiness and calmness. The addiction/dependence potential of Imipramine is very less. It may be extremely dangerous in overdose.
Q. Is Imipramine a monoamine oxidase inhibitor/ anticholinergic/ tricyclic antidepressant/benzodiazepine?
Imipramine belongs to a class of medication called tricyclic antidepressants. It is not a monoamine oxidase inhibitor/ anticholinergic/ benzodiazepine
Q. Is Imipramine addictive?
No, Imipramine is not addictive
Q. Is Imipramine sedative?
It had sedative effect, due to its antihistaminergic effect
Q. Is Imipramine good for anxiety?
Yes, Imipramine may be used for the treatment of anxiety (panic disorder).
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