Side Effects:

Common Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.

Expert advice for Defenac Tablet SR
It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Defenac can raise a risk of blood clots, heart attack, or a stroke. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Frequently Asked Questions

Q. Can Defenac be used along with warfarin?
No. Using Defenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.

Q. Is Defenac a painkiller?
Yes. Defenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.

Q. Is Defenac a narcotic?
No, Defenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Can I use Defenac along with vitamins?
Yes, Defenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Can Defenac be used for the treatment of hepatitis?
No, Defenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Defenac can, in fact, cause harm to the liver as a side effect.

Q. Can Defenac be used after C-section?
Yes, Defenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Defenac can be used to treat the pain that may occur after the operation.

Q. Can I take Defenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Defenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).

Q. Can I take Defenac while I am on thyroxine?
Yes, Defenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Why Defenac should be stopped before surgery?
Since Defenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.

Q. What are the contraindications for Defenac?
Defenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.

Q. Can Defenac affect the chance of conceiving?
Yes. Defenac can sometime cause reversible infertility. Defenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Why does Defenac cause an ulcer?
Defenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.

Q. Why is Defenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Is Defenac good for back pain?
Yes, Defenac has been found to be effective to reduce back pain. Defenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.

Q. Can I use Defenac during my fever treatment?
Yes, Defenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.

Q. Can I use Defenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Defenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.

Q. Can I use Defenac to treat urinary tract infections (UTI)?
Defenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.

Q. Can Defenac cause sedation?
Defenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.

Q. Can I take Defenac for kidney stones?
Yes,Defenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Defenac as its side effect. It is advised not to take Defenac for a prolonged time for this condition without adequate monitoring.

Q. Can I use Defenac for the treatment of arthritis?
Yes, Defenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .

Q. Can I use Defenac with diuretics?
No, Defenac should not be used with diuretics. Defenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can I use Defenac with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Defenac. Mifepristone is used for medical abortion.

Q. Can I use Defenac with lithium?
No.These drugs should not be used together as Defenac increases the blood levels of lithium which may further increase the side effects.