Denex Forte 450 mg/300 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

Denex Forte 450 mg/300 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Denex Forte 450 mg/300 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

Do not drive unless you are feeling well.Denex Forte 450 mg/300 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.

Denex Forte 450 mg/300 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Denex Forte 450 mg/300 mg Tablet may be needed. Please consult your doctor.

Denex Forte 450 mg/300 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Denex Forte 450 mg/300 mg Tablet may be needed. Please consult your doctor.Use of Denex Forte 450 mg/300 mg Tablet is not recommended in patients with severe liver disease.