Side Effects:

Common Nausea, Abdominal pain, Constipation, Flatulence, Diarrhoea.

Common Dryness in mouth.

Expert advice for Cucid Oral Gel
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Cucid can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.  Inform your doctor if you are suffering from osteoporosis as Cucid can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate. Cucid is a well-tolerated medicine and provides relief for a long time. It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them. Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Expert advice for Domperidone

Do not take Domperidone, if you are allergic to it or to any other content in the tablets.
Do not take the medicine, if you notice black, tarry stools (bowel motions) or blood in your stools, blockage or tear in the intestines or if you have a tumor of the pituitary gland (prolactinoma).
Do not take the drug, if you have moderate to severe liver disease, heart problems (irregular heart rate or heart failure) or abnormal salt levels in the blood.
Do not crush or chew the tablets, swallow them whole with a glass of water.
Do not take the drug if you intend to drive or operate heavy machinery as it may cause drowsiness.
Always take the tablets 15 to 30 minutes before meals and, if needed, before going to bed at night.
Consult your doctor, if you are above 60 years of age and taking domperidone for a long period of time.
Inform your doctor, if you are already taking medicines for fungal infections (ketoconazole) or antibiotics (e.g. gentamycin, erythromycin).

Frequently Asked Questions

Q. Can I take Cucid with domperidone?
Cucid can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. What are the various conditions in which the use of Cucid is contraindicated?
Use of Cucid is contraindicated if you are allergic to this medicine or any other medicine belonging to the same class of drugs. Also, do not take Cucid if you are already taking a medicine containing nelfinavir (used for the treatment of HIV infection).

Q. What if I miss my dose of Cucid?
If you miss a dose of Cucid, take it as soon as you remember and the next dose as scheduled. However, if it is almost the time for your next dose, skip the missed dose and take your next dose and then follow the regular schedule. Do not take double the dose.

Q. Can I take Cucid along with oral contraceptive pills (birth control pills)?
Cucid can be safely taken with oral contraceptive pills (birth control). They do not affect each other's action and no harmful effects have been seen when they are used together.

Q. What is Cucid?
Cucid belongs to the group of medicines known as proton pump inhibitors (PPIs). This drug decreases the acid production in your stomach and is indicated for the treatment of conditions caused by excess acid secretion in the stomach.

Q. Can Cucid cause subacute cutaneous lupus erythematosus?
Cucid has been reported to cause subacute cutaneous lupus erythematosus in many studies. Common signs and symptoms of this disease include painful joints, tiredness, weakness, rash, fever, anemia, mouth ulcers, hair loss, and many others and these may get aggravated again and again. Talk to your doctor if you experience these side effects as you may need to discontinue this medicine.

Q. Can I take Cucid with ondansetron?
Ondansetron is an anti-emetic medicine which helps in relieving nausea (feeling sick) or vomiting. No harmful effects have been seen when Cucid is used with ondansetron. So, these two medicines can be taken together.

Q. Can Cucid cause lactose intolerance?
Lactose intolerance has been reported with the use of Cucid in some patients. Many Cucid preparations contain lactose as an ingredient. This is a digestive problem in which the patient cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.

Q. Can I take Cucid with Vitamin E?
Cucid can be taken with vitamin E. The combinations seems to have a beneficial effect in terms of better maintenance of moderate to severe esophagitis. However, there are not many studies or reports on this subject. Talk to your doctor for more information on this.

Q. Can I take Cucid with levosulpiride?
Cucid can be safely taken with levosulpiride as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Levosulpiride works by increasing the gut motility and Cucid decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Does Cucid use increase the risk of clostridium difficile infection?
Use of proton pump inhibitors (PPIs) like Cucid may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD) as reported in few studies and informed by the US FDA as well. A possibility of CDAD can be there in patients taking PPIs and developed diarrhea that does not improve.

Q. Can Cucid be used in cancer patients?
Cucid can be taken by cancer patients as prescribed by a doctor. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with Cucid.

Q. For how long can Cucid be taken?
Take Cucid for as long as advised by your doctor. The duration of taking Cucid would vary depending on your condition. Do not stop taking this medicine without talking to your doctor.

Q. Can Cucid cause calcium deficiency and osteoporosis?
Cucid can cause osteoporosis (thinning of bones) as it decreases the calcium absorption leading to calcium deficiency. This leads to an increased risk of bone fractures on long-term use, like hip, wrist or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Q. What are the rare side effects of Cucid?
Rare side effects seen with the use of Cucid includes a decrease in white cells or platelets, allergic reactions, problems like blurred vision, wheezing, shortness of breath (bronchospasm), dry mouth, thrush, liver problems like jaundice, hair loss (alopecia), skin rash on exposure to sunshine, joint pains (arthralgia) or muscle pains (myalgia), severe kidney problems (interstitial nephritis), increased sweating and inflammation of the gut causing diarrhoea.

Q. How does Cucid work?
Proton (acid) pumps are found on the stomach mucosa and they are responsible for secreting acid in the stomach. Cucid works by blocking this gastric acid pump and this unique mechanism of action helps in decreasing the acid secretion in the stomach.

Q. Does Cucid cause hepatitis B and can a patient of hepatitis take Cucid?
Cucid can rarely cause hepatitis with or without jaundice and very rarely it can lead to hepatic failure and encephalopathy in patients with the underlying liver disease. Cucid does not cause hepatitis B or any other viral hepatitis. However, there are studies showing an increased occurrence of hepatic encephalopathy in hepatitis B patients using PPIs. These medicines should be used with caution in patients with the underlying liver disease.

Q. Does Cucid increase chromogranin levels?
Use of proton pump inhibitors like Cucid has been seen to be associated with an increase in chromogranin levels. This increase in chromogranin levels can be due to the effect of these drugs on enterochromaffin cells and this could also falsely increase the levels in patients with neuroendocrine tumours.

Q. Does Cucid cause dementia?
Use of proton pump inhibitors like Cucid has been recently linked with the development of dementia in elderly patients. As this risk of developing dementia is not confirmed, talk to your doctor for more information on this effect.

Q. Does Cucid cause vitamin deficiencies?
Cucid may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while Cucid causes a decrease the gastric acid secretion. You may need to take vitamin B12 supplements from outside. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.

Q. Does Cucid have an expiry date?
Yes, Cucid does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Cucid after the expiry date.

Q. What is the role of Cucid before endoscopy in patients with gastrointestinal bleeding?
Cucid before endoscopy in patients with gastrointestinal bleeding reduces the need for endoscopic therapy, the rate of post-endoscopy bleeding, and shortens hospital stays. Hence Cucid is given before endoscopy in patients with gastrointestinal bleeding.

Q. Are there any withdrawal symptoms associated with the use of Cucid?
There are no withdrawal symptoms seen when patients stop using Cucid as it has no habit forming tendencies.

Q. Can Cucid cause magnesium deficiency?
Cucid can cause magnesium deficiency in the blood. Low magnesium levels is a rare side effect seen in patients treated with Cucid for at least three months and in most cases after a year of therapy. The patient may have symptoms like tetany, arrhythmias, and seizures and may need to stop this medicine and take magnesium from outside. Magnesium levels should be tested at regular intervals in the patients taking Cucid for a long duration.

Q. Is Cucid a controlled substance?
Cucid is not a controlled substance. It is available when prescribed by a doctor.

Q. Can Cucid be used in cardiac patients?
Patients with cardiac disease can take Cucid. However, Cucid can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with an underlying cardiac disease. Patients taking Cucid and digoxin may need to be monitored for digoxin toxicity. Cucid decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored closely by a doctor.

Q. Can the use of Cucid cause iron deficiency?
Use of Cucid can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Cucid.

Q. Is Cucid a narcotic substance?
Cucid is a not a narcotic substance and has not been reported to have any abuse potential. Cucid does not get you high and does not cause any addiction as no withdrawal symptoms have been reported when you stop taking this drug.

Q. Is Cucid available without a prescription as an over the counter product?
Cucid is a prescription medicine and you can buy this drug by providing a doctor's prescription. Cucid is not available as an over the counter (OTC) product.

Q. How is Cucid metabolised in the body?
Cucid is metabolized in the liver by the cytochrome P450 enzymes mainly CYP2C19. There could be an increase in the level of Cucid in patients with underlying liver disease because of a decrease in its metabolism. However, the amount of drug does not increase if given once a day.

Q. Can Cucid be used in stroke patients?
Cucid can be used in stroke patients. There are studies suggesting that proton-pump inhibitors (PPIs) as a class are not associated with an increased short-term risk of recurrent stroke or death among older adults treated with clopidogrel after stroke.

Q. What is Domperidone used for?
Domperidone is used for the treatment of nausea (feeling sick) and vomiting as and when recommended by your doctor.

Q. Is Domperidone an over the counter drug?
Domperidone is not an over the counter (OTC) medicine and it is not advisable to take it without a prescription.

Q. Does Domperidone cause weight gain?
Weight gain has not been reported with the use of Domperidone. If you notice any abnormal weight gain while using Domperidone, please talk to your doctor.

Q. Does Domperidone raise the blood pressure?
The increase in blood pressure is generally not seen with the use of Domperidone. But if you experience an increase in blood pressure while using Domperidone, please consult your doctor.

Q. Can I take Domperidone for morning sickness?
Domperidone is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness.

Q. Can I take Domperidone with antibiotics?
The use of Domperidone with antibiotics like erythromycin, levofloxacin, moxifloxacin, spiramycin, and some antifungals is not recommended. Please consult your doctor before using any antibiotics with Domperidone.

Q. Can I take Domperidone with lansoprazole?
Yes, Domperidone can be taken with lansoprazole as no drug-drug interactions have been clinically seen when they are taken together. However, interactions may occur. Please consult your doctor before using the two medicines together.

Q. Can I take Domperidone with doxycycline?
Yes, Domperidone can be taken with doxycycline. No drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with doxycycline.

Q. Can I take Domperidone with omeprazole?
Yes, Domperidone can be taken with omeprazole. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor before using the two medicines together.

Q. Can I take Domperidone with citalopram?
The use of Domperidone with citalopram is not recommended as it may increase the underlying heart problems like prolonged QTc interval. Please consult your doctor before taking the two medicines together.

Q. Can I take Domperidone with amitriptyline?
Yes, Domperidone can be taken with amitriptyline. No drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with amitriptyline.

Q. Can I take Domperidone with amoxicillin?
Yes, Domperidone can be taken with amoxicillin. No drug-drug interactions have been reported. However, please consult your doctor before taking Domperidone with amoxicillin.

Q. Can I take Domperidone with paracetamol?
Yes, Domperidone can be taken with paracetamol. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor.

Q. Can I take Domperidone with tramadol?
Yes, Domperidone can be taken with tramadol as no drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with tramadol.

Q. Is Domperidone safe?
Yes. Domperidone is safe if used at prescribed doses for the prescribed duration as advised by the physician/ doctor.

Q. Is Domperidone used for motion sickness?
Domperidone is indicated for use in motion sickness. Please consult your doctor before using Domperidone for motion sickness as it must be used in the dose and duration as advised by your doctor.

Q. Is Domperidone an antibiotic?
No, Domperidone is not an antibiotic. Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick).

Q. Does Domperidone cause drowsiness?
Drowsiness has been reported as one of the rare side effects with Domperidone. Please talk to your doctor if you experience excessive drowsiness while taking Domperidone.

Q. Does Domperidone increase milk secretion?
Yes, Domperidone can increase milk secretion also known as galactorrhea. This is an uncommon side effect of Domperidone. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Q. Does Domperidone cause bloating (gas)?
Domperidone can cause some uncommon gastrointestinal side effects like regurgitation, appetite disorder, and heartburn, diarrhoea. However, bloating (gas) has not been reported as a side effect with Domperidone.

Q. Does Domperidone cause hair loss?
Domperidone has not been reported to cause hair loss. Please consult your doctor in case you experience excessive hair loss while taking Domperidone.

Q. Does Domperidone help to treat constipation?
Domperidone is not indicated to treat constipation. Please talk to your doctor regarding its use.

Q. Does Domperidone cause heart problems?
Domperidone may be associated with an increased risk of heartbeat problem and heart attack. This risk may be more likely in those over 60 years old or taking higher doses. The risk also increases when Domperidone is given together with other medicines. Please share your medical history with your doctor if you are prescribed Domperidone.

Q. Does Domperidone cause constipation?
Yes, Domperidone has been seen to cause constipation as a side effect.Consult your doctor if you experience excessive constipation while using Domperidone.

Q. Does Domperidone help to relieve bloating (gas)?
Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick). It is not indicated to treat bloating (gas). Please consult your doctor before using this medicine.

Q. Can I take Domperidone with rabeprazole?
Domperidone can be safely taken with Rabeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.