Common Edema, Abdominal bloating, Anxiety, Irritability, Depression, Muscle pain.

Expert advice for Endofit Tablet
• Inform your doctor if you or close relatives of yours have the propensity to form blood clots, e.g clots in blood vessels of leg, lungs, or have experienced heart attack, stroke, or suffer from compromised blood supply to any part of the body, especially hands and legs.
• Tell your doctor if your close relative has or has had breast cancer.
• Seek immediate medical attention if you notice possible signs of a blood clot such as a blood clot in the leg (pain, swelling, redness, discoloration of the leg), a blood clot in the lung (pulmonary embolism; breathlessness, wheezing, irregular heartbeats, cough, dizziness etc.), a heart attack or a stroke. 
•Tell your doctor if you have a disease that first appeared during pregnancy or earlier use of sex hormones, such as  hearing loss, porphyria (a disease of the blood), gestational herpes (skin rash with blisters during pregnancy) or Sydenham’s chorea (a nerve disease causing sudden, uncontrolled movements of the body).
• Seek immediate medical attention if you experience symptoms of angioedema/allergy such as swollen face, tongue and/or throat and/or difficulty swallowing or itchy rash, together with difficulty breathing. 
• Tell your doctor if you are pregnant or breastfeeding or if you have just given birth. 
• Patients allergic to dienogest or any of its ingredients should not be given dinigest.
• Women with presence or risk of venous thromboembolism (blood clots in blood vessels of the leg or lungs) should avoid it.
• Women undergone any major surgery with prolonged immobilization should avoid dienogest intake.
• Women with presence or risk of arterial thromboembolism (blood clots in arteries, causing compromised blood supply to heart, brain, hands, and legs) should avoid it.

Q. Is dienogest antiandrogenic?
Dienogest has an antiandrogenic activity and mainly act by blocking the action of testosterone

Q. Is dienogest as effective as leuprolide or triptorelin?
Apart from its indication as oral contraceptive, dienogest is also indicated for endometriosis (a condition resulting from the appearance of endometrial tissue outside the womb and causing pelvic pain, especially associated with menstruation). Dienogest is as effective as leuprolide and triptorelin in the treatment of endometriosis.