Side Effects:

Common Dizziness, Headache, Confusion, Constipation.

Expert advice for Ebixa Tablet
Ebixa slows down the progression of the disease; it doesn't stop or reverse it. Inform your doctor if you have ever been diagnosed with any heart problems (high blood pressure, heart attack, heart failure, slow or irregular heart rate). Inform your doctor if you have ever been diagnosed with any epileptic seizures. Ebixa may raise the chances of seizure if you had in the past. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Frequently Asked Questions

Q. Is Ebixa a psychotropic drug?
A psychotropic drug is a medicine affecting the mind, emotions, and behaviour. Ebixa has a beneficial effect on the behavioural symptoms of patients with moderate to severe Alzheimer's Disease. Therefore it is considered as a psychotropic agent.

Q. Is Ebixa a narcotic?
No. Ebixa is not a narcotic. It does not have habit forming potential.

Q. Is Ebixa a mood stabiliser?
No. Mood stabilisers are used to treat mania and bipolar disorder. Ebixa is not approved for these conditions yet, although studies are going on for the role of Ebixa in these diseases also.

Q. Is Ebixa a nootropic.
No. Ebixa does not fit in the generally accepted "Nootropic" descriptor for healthy people. Nootropics are drugs which increase cognition/ motivation/ creativity in healthy individuals. Ebixa, on the other hand, improves cognition in patients with Alzheimer's Disease.

Q. Is Ebixa a cholinesterase inhibitor?
No. Ebixa does not function by inhibiting the cholinesterase enzyme found in the endings of nerve cells. Rather, it acts by preventing the toxicity of an excitatory substance called glutamate in the brain.

Q. Is Ebixa a NMDA receptor antagonist?
Yes. Ebixa acts as an antagonist at the NMDA receptor. This is the receptor in the brain through which glutamate, an excitatory substance, damages the nerve cells in the brain, which is found in Alzheimer's disease.

Q. What is Cmax of Ebixa?
Cmax (Peak plasm concentration) of Ebixa is 35-40 ng/ml.

Q. Can I take Ebixa with vitamin D?
It has been reported in some studies that a combination of Ebixa and Vitamin D improves cognition in Alzheimer's Disease. However, more studies are required to confirm this finding.

Q. Can I take Ebixa with vitamin E?
Some studies have reported that among patients with mild to moderate Alzheimer's disease, taking alpha-tocopherol (Vitamin E) with Ebixa slows the progressive functional decline. However, more studies are required to confirm this finding.

Q. When to start Ebixa?
Ebixa is started when a person starts suffering from moderate to severe Alzheimer's Disease and has failed other options. Despite years of research for mild Alzheimer's Disease, Ebixa has not been found to be useful in it.

Q. Why is Ebixa prescribed?
Ebixa is prescribed to improve the cognitive (memory) function in patients with Alzheimer's Disease when other treatment options like cholinesterase enzyme inhibitors have failed.

Q. What is the interaction of Ebixa with metformin?
The interaction between Ebixa and Metformin is minor. Ebixa oral increases the level or effect of metformin by nonacidic drugs competing for the same pathway through the kidney.

Q. What is the interaction of Ebixa with warfarin?
No known interaction between Ebixa and Warfarin has been found.

Q. Can Ebixa used in dementia with Lewy bodies?
The role of Ebixa in Lewy Body Dementia (LBD) is controversial. Some studies suggest that it is safe and efficacious in this disease whereas others have shown exacerbation of LBD due to Ebixa. Ebixa is not approved for use in Lewy Body Dementia.

Q. Can Ebixa combined with donepezil?
A combination of Ebixa and Donepezil can be given in moderate to severe Alzheimer's Disease. It has been shown that the combination may have additive effects i.e. effects of both drugs are added when given together in some studies.

Q. Can Ebixa be used with rivastigmine?
Ebixa in combination with rivastigmine is safe and beneficial in patients with Alzheimer's Disease. Patients have improvement or stabilisation on dual therapy.

Q. Can Ebixa be used for chronic pain?
Ebixa is not indicated for use in chronic pain. It has been proposed as a medication for the treatment of neuropathic pain for its mechanism, safety, lack of serious adverse effects, and the relatively rapid onset of action. However, studies have not been promising so far and its routine use in neuropathic pain is not currently recommended.

Q. Can Ebixa be used for opiate withdrawal?
Ebixa is not indicated for use in Opioid withdrawal. In a number of small studies, it has been seen that Ebixa decreased the expression of opioid physical dependence in humans but there is a need for more studies in this field.

Q. Can Ebixa be used for autism?
Ebixa has failed to demonstrate clinical efficacy in autism. Studies are currently in progress for other clinical applications.

Q. Can Ebixa use for dementia?
Ebixa has failed to demonstrate clinical efficacy in vascular dementia although it was well-tolerated.