Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

Frusis 20 mg/50 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Frusis 20 mg/50 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Frusis 20 mg/50 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Frusis 20 mg/50 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Frusis 20 mg/50 mg Tablet may be needed. Please consult your doctor.Use of Frusis 20 mg/50 mg Tablet is not recommended in patients with severe kidney disease.

Frusis 20 mg/50 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Frusis 20 mg/50 mg Tablet may be needed. Please consult your doctor.