Stimin G 0.5 mg/2.5 mg Injection 
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NOTICE: unsafe with : Alcohol
USED FOR:
Anaesthesia
Myasthenia gravis
COMPOSITION:
Glycopyrrolate (0.5mg)
Neostigmine (2.5mg)
Therapeutic Uses:
gastro intestinal
neuro cns
CAUTION
Stimin G 0.5 mg/2.5 mg Injection may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Stimin G 0.5 mg/2.5 mg Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Stimin G 0.5 mg/2.5 mg Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.Long-term use of Stimin G 0.5 mg/2.5 mg Injection might reduce milk production.
Do not drive unless you are feeling well.Stimin G 0.5 mg/2.5 mg Injection may affect vision and coordination. This may affect your driving ability.
CAUTION
Stimin G 0.5 mg/2.5 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Stimin G 0.5 mg/2.5 mg Injection may be needed. Please consult your doctor.Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Stimin G 0.5 mg/2.5 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Stimin G 0.5 mg/2.5 mg Injection may not be needed in these patients. Please consult your doctor.
Uses of Glycopyrrolate
Glycopyrrolate is used in Anaesthesia.
How to use Glycopyrrolate
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Stimin G 0.5 mg/2.5 mg Injection works
Glycopyrrolate belongs to a class of medications called anticholinergics. It decreases the secretions in the mouth, throat, airways and stomach acid.
Common Visual disturbance, Reduced sweating, Irregular heartbeats, Dryness in mouth, Nausea, Vomiting, Dry skin, Photophobia, Flushing (sense of warmth in the face, ears, neck and trunk), Giddiness, Difficulty in urination, Confusion.
Expert advice for Glycopyrrolate
Inform your doctor if you have any heart disease, heart failure, irregular heartbeats or high blood pressure as glycopyrrolate is known to increase the heart rate (tachycardia).
Glycopyrrolate should be used with caution if you have medical conditions such as myasthenia gravis (progressive neuromuscular disease characterized by weak muscles and unusual tiredness), glaucoma (increased pressure in the eye that causes vision problem), overactive thyroid gland, enlarged prostate gland, obstruction of the stomach or bowel causing vomiting  abdominal pain, chronic constipation and swelling.
Glycopyrrolate should be used with special precautions in case of fever as it may worsen the condition.
Avoid alcohol or any medication that may cause drowsiness.Â
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Do not take if allergic to glycopyrrolate or any of its ingredients.
Q. Is Glycopyrrolate used for excessive sweating?
Glycopyrrolate is the most commonly used medicine for managing excessive sweating due to its anti-secretory or anticholinergic effect
Q. Is Glycopyrrolate the same as glycopyrronium bromide?
Yes, Glycopyrrolate is same as glycopyrronium bromide
Q. Does Glycopyrrolate affect fertility & birth control?
No, Glycopyrrolate is not known to impair fertility and has no known effects on birth control
Q. Is Glycopyrrolate over the counter?
No, Glycopyrrolate is strictly prescribed by the doctors.
Uses of Neostigmine
Neostigmine is used in the treatment of myasthenia gravis, paralytic ileus, post-operative urinary retention and reversal of effect of skeletal muscle relaxant after surgery.
How to use Neostigmine
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Stimin G 0.5 mg/2.5 mg Injection works
Neostigmine increases the levels of chemical messengers which allows free transmission of signals across the nerves and muscles.
Common Nausea, Vomiting, Abdominal cramp, Diarrhoea, Excessive salivation.
Expert advice for Neostigmine
You may need to stop using the medicine for a short time in case of a surgery.
Use neostigmine with caution if you have epilepsy, bronchial asthma, bradycardia, recent coronary occlusion, vagotonia, hyperthyroidism, cardiac arrhythmias, peptic ulcer.
Avoid taking large doses of neostigmine in situations where there might be an increased absorption rate from the intestinal tract. Use with caution when neostigmine is given along with anticholinergic drugs because of decreased GI motility.
Do not drive or operate machinery as neostigmine can cause blurred vision or impaired thinking.
Do not drink alcohol while taking neostigmine as it may worsen the side effects.
Take precautions while taking neostigmine as over dosage of neostigmine can cause extreme muscle weakness.
Q. Is neostigmine an anticholinesterase/ anticholinergic/agonist/ cholinesterase inhibitor/ neurotransmitter?
Neostigmine is an anticholinesterase. But, it is not an anticholinergic, agonist, cholinesterase inhibitor or a neurotransmitter
Q. Does neostigmine cause nausea?
Yes, neostigmine causes mild nausea
Q. Does neostigmine reverse rocuronium/ reverse succinylcholine / inhibit pseudocholinesterase / cause histamine release?
Yes, Neostigmine causes reversal of rocuronium/ succinyl choline and inhibits pseudocholinesterease. It also causes histamine release.
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