Gemita 1400 mg/87.5 mg Injection 
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NOTICE: unsafe with : Lactation
USED FOR:
Ovarian cancer
Acute renal failure
Head and neck cancer
COMPOSITION:
Gemcitabine (1400mg)
Mannitol (87.5mg)
Therapeutic Uses:
anti neoplastics
cardiac
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Gemita 1400 mg/87.5 mg Injection is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
UNSAFE
Gemita 1400 mg/87.5 mg Injection is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Gemita 1400 mg/87.5 mg Injection may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Gemita 1400 mg/87.5 mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Gemita 1400 mg/87.5 mg Injection may not be needed in these patients. Please consult your doctor.
There is limited information available on the use of Gemita 1400 mg/87.5 mg Injection in patients with liver disease. Please consult your doctor.
Uses of Gemcitabine
Gemcitabine is used in the treatment of ovarian cancer, head and neck cancer, cervical cancer, Testicular cancer., breast cancer, non-Hodgkin lymphoma (NHL), blood cancer, lung cancer, bone cancer and urinary bladder cancer.
How to use Gemcitabine
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Gemita 1400 mg/87.5 mg Injection works
Gemcitabine interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Common Nausea, Vomiting, Loss of appetite, Hair loss, Reduced blood platelets, Allergic reaction, Breathlessness, Decreased white blood cell count, Increased liver enzymes, Anemia, Influenza like symptoms, Blood in urine, Skin rash, Protein in urine.
Expert advice for Gemcitabine
Not recommended in children or adolescents below 18 years of age.
Inform your doctor if you have history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression).
Inform your doctor if you have breathing problems or feel weak and pale as this could be a sign of kidney dysfunction; unexplained new or worsening dyspnea or evidence of severe pulmonary toxicity.
Take precautions if you are on a controlled sodium diet, as this medicine contains some amount of sodium.
You should undergo blood count, heart/kidney/liver function tests before therapy.
Do not take live or attenuated vaccines during therapy and avoid contact with persons who receive them.
Alcohol is an ingredient of this infusion. If you are suffering from alcoholism or epilepsy, you may have serious side effects. Other medication taken at this time may have altered effects.Â
Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies.Â
They should use two effective methods of contraception while on this therapy and 6 months after it.
Men who are going to use this therapy should not father a child while on this therapy and 6 months after it. They should also seek guidance and counselling on sperm conservation before taking this therapy.
Do not drive or use machinery after taking this drug as it may cause sleepiness which may worsen with alcohol use.
Q. Is Gemcitabine a vesicant/ anthracycline/ prodrug?
Gemcitabine is not a vesicant/ anthracycline/ prodrug
Q. Does Gemcitabine cause hair loss or abdominal pain?
Yes, Gemcitabine has hair loss and abdominal pain as side effects. Please consult your doctor immediately if you experience such side effects
Q. Is Gemcitabine a cytotoxic or chemotherapy agent?
Yes, Gemcitabine is a cytotoxic chemotherapy agent
Q. Does Gemcitabine work in pancreatic cancer?
Yes, Gemcitabine is used to treat pancreatic cancer.
Uses of Mannitol
Mannitol is used in the treatment of acute renal failure, cerebral edema and glaucoma.
How to use Mannitol
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Gemita 1400 mg/87.5 mg Injection works
Mannitol is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Mannitol is also used to lower the pressure inside the eye or swelling around the brain.
Common Nausea, Vomiting, Headache, Dehydration.
Expert advice for Mannitol
Tell your doctor if you have swelling, kidney problems, or heart problems (e.g., congestive heart failure).
Exercise caution in children <12 years and if you are an elderly patient.
Seek immediate medical attention if you have difficulty urinating or extreme dizziness.
You will be regularly monitored for lab tests such as blood electrolytes, kidney function, lung function, heart function and blood counts.
Do not drive or use any machinery after taking mannitol as it may cause dizziness.
Do not consume alcohol when on treatment with mannitol, as it may worsen its side effects.
Tell your doctor if you are planning or planning to become pregnant or are breastfeeding.
Do not take if allergic to mannitol or any of its ingredients.
Do not take in pre-existing plasma hyperosmolarity.
Do not take in severe dehydration, established anuria (failure of the kidneys to produce urine), severe heart failure, severe lung congestion or oedema, active intracranial bleeding (bleeding within the cranial vault), except during craniotomy (surgical removal of part of the bone from the skull to expose the brain).
Do not take if suffering from disturbance of the blood-brain barrier.
Do not take if suffering from progressive renal damage or dysfunction after institution of mannitol therapy, including increasing oliguria and azotemia (elevation of blood urea nitrogen).
Q. Is Mannitol a sugar?
Mannitol is a polyol (sugar alcohol)
Q. Is Mannitol salt agar selective?
Yes, Mannitol salt agar is a selective, differential and Indicator medium.
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