G Kelfin 25 mg/500 mg Tablet 
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USED FOR:
Malaria
Bacterial infections
COMPOSITION:
Pyrimethamine (25mg)
Sulfamethoxazole (500mg)
Therapeutic Uses:
anti malarials
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
G Kelfin 25 mg/500 mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
SAFE
G Kelfin 25 mg/500 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.There may be a possibility of skin rash in the baby
It is not known whether G Kelfin 25 mg/500 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
G Kelfin 25 mg/500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of G Kelfin 25 mg/500 mg Tablet may be needed. Please consult your doctor.
CAUTION
G Kelfin 25 mg/500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of G Kelfin 25 mg/500 mg Tablet may be needed. Please consult your doctor.
Uses of Pyrimethamine
Pyrimethamine is used in the treatment of malaria.
How to use Pyrimethamine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
How G Kelfin 25 mg/500 mg Tablet works
Pyrimethamine is a weak base that reaches high concentration within the malarial parasite and causes accumulation of toxic heme pigment, which kills it.
Common Abnormal bruising, Abnormal skin pigmentation, Anemia, Change in blood test results, Dizziness, Headache, Vomiting, Weakness, Diarrhoea, Nausea.
Expert advice for Pyrimethamine
Pyrimethamine when given with sulphonamide, it should be given with folic acid (vitamin) supplement.
Do not use pyrimethamine if you are allergic to pyrimethamine or any other ingredient.
Do not take pyrimethamine if you have megaloblastic anemia due to folate deficiency.
Do not take pyrimethamine if you have kidney or liver problems; fits (seizures); depression; bone marrow problems; stomach or bowel problems (eg, malabsorption syndrome); phenylketonuria, or alcoholism.
Q. What is Pyrimethamine is used for?
Pyrimethamine is used to treat toxoplasmosis and treat or prevent malaria infections along with other medicines
Q. How does Pyrimethamine work?
Pyrimethamine is an antiparasitic and works by killing the parasites or preventing their growth in the blood stream.
Uses of Sulfamethoxazole
Sulfamethoxazole is used in the treatment of bacterial infections.
How to use Sulfamethoxazole
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
How G Kelfin 25 mg/500 mg Tablet works
Sulfamethoxazole is an antibiotic. It stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.
Common Nausea, Vomiting, Skin rash, Allergic reaction.
Expert advice for Sulfamethoxazole
Do not take further dose of taking sulfamethoxazole and consult your doctor at the first appearance of a skin rash, sore throat, fever, muscle, joints, bone pain or stiffness (arthralgia), cough, shortness of breath or jaundice.
Avoid excessive exposure to sunlight and wear sunscreen when going out.
Drink adequate water during sulfonamide therapy.
Do not start or continue the sulfamethoxazole tablets and consult your doctor If  you are pregnant or breast-feeding.
Q. Is Bactrim/Septrin/septran/ ciplin, sulphamethoxazole + trimethoprin a sulfa drug, penicillin, antibiotic?
Bactrim/Septrin/septran/ciplin are brand names for sulphamethoxazole + trimethoprin combination belongs to class of medications called sulfonamide antibiotic, it is a sulpha drug. Sulphamethoxazole + trimethoprin is not a penicillin antibiotic
Q. Is Sulphamethoxazole + trimethoprin combination safe?
Sulphamethoxazole + trimethoprin is relatively safe if used as recommended. In case of any side effects, consult your doctor
Q. What is sulphamethoxazole + trimethoprim used for?
Sulphamethoxazole + trimethoprim is used to treat or prevent lung infections, sinus infection, toxoplasmosis, nocardiosis (bacterial infection causing abscesses), urinary tract infections, bronchitis, ear infections
Q. Can I take sulphamethoxazole + trimethoprim with Tylenol/acetaminophen, Aleve/naproxen, Benadryl, prednisone, Adderall/amphetamine/dextroamphetamine, Xanax/alprazolam, Valtrex/valacyclovir, antacids, vitamins, aspirin?
Interaction is not observed, when sulphamethoxazole + trimethoprim is taken with acetaminophen, naproxen, Benadryl, prednisone, amphetamine and dextroamphetamine, alprazolam, valacyclovir, antacids, vitamins, aspirin however do consult your doctor before use
Q. Can I take Interaction is not observed with birth control pills?
Interaction is not observed when sulphamethoxazole + trimethoprim is taken with birth control pills. Please consult your doctor before use
Q. Does sulphamethoxazole + trimethoprim make you tired, cause headache?
Sulphamethoxazole + trimethoprim can make you tired and can cause headache.
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