Hycamtin 1mg Tablet 
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NOTICE: unsafe with : Lactation
USED FOR:
Ovarian cancer
Small cell lung cancer
Cervical cancer
COMPOSITION:
Topotecan (1mg)
Therapeutic Uses:
anti neoplastics
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Hycamtin 1mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
UNSAFE
Hycamtin 1mg Tablet is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Do not drive unless you are feeling well.Hycamtin 1mg Tablet can make you feel tired and this may affect your ability to drive.
CAUTION
Hycamtin 1mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hycamtin 1mg Tablet may be needed. Please consult your doctor.Use of Hycamtin 1mg Tablet is not recommended in patients with end-stage kidney disease.
SAFE
Hycamtin 1mg Tablet is safe to use in patients with liver disease. No dose adjustment of Hycamtin 1mg Tablet is recommended.
Uses of Hycamtin Tablet
Hycamtin 1mg Tablet is used in the treatment of ovarian cancer, small cell lung cancer, cervical cancer and cancer of colon and rectum.
How to use Hycamtin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hycamtin 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Hycamtin Tablet works
Hycamtin 1mg Tablet is an anti-cancer medication. It is an inhibitor of topoisomerase, an enzyme important for replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Common Fatigue, Nausea, Vomiting, Hair loss, Reduced blood platelets, Anemia, Infection, Decreased white blood cell count (neutrophils), Fever, Mucosal inflammation, Weakness, Diarrhoea, Decreased white blood cell count, Decreased appetite, Abdominal pain, Constipation.
Expert advice for Hycamtin Tablet
Before you take topotecan, inform your doctor if have /are being treated for kidney disease.If you are undergoing a surgery including dental surgery, do inform your doctor that you are being treated with topotecan.Do not drive or operate machinery as topotecan may cause tiredness, drowsiness or weakness.Take precautions while using topotecan as it may cause severe diarrhea requiring hospitalization.You should get your blood count monitored regularly to check for any signs of serious infections.Stop using topetecan and immediately report any pulmonary symptoms indicative of interstitial lung disease (e.g. cough, fever, dyspnoea and/or hypoxia).Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Q. How often is Hycamtin given?
Generally Hycamtin treatment is for 4 cycles of 21 day each, patient is given Hycamtin for first 5 days of each cycle
Q. Does Hycamtin cause hair loss?
Yes, Hycamtin may cause temporary hair loss
Q. Does Hycamtin cause flare reaction?
Yes, Hycamtin may cause flare reaction
Q. How long does Hycamtin take to work?
The drug may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles
Q. Is Hycamtin a vesicant?
Hycamtin is a vesicant (irritant)
Q. Is Hycamtin effective/ effective in ovarian cancer?
Yes Hycamtin is effective if used at prescribed doses for the prescribed duration as advised by your doctor
Q. What is Hycamtin chemotherapy?
It is a treatment therapy that includes Hycamtin with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer)
Q. How is Hycamtin administered?
Hycamtin is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.
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