Vaxone S 1.5gm Injection 
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NOTICE: unsafe with : Alcohol
USED FOR:
Bacterial infections
COMPOSITION:
Cefoperazone (1000mg)
Sulbactam (500mg)
Therapeutic Uses:
anti infectives
CAUTION
Vaxone S 1.5gm Injection may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
PROBABLY SAFE
Vaxone S 1.5gm Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
SAFE
Vaxone S 1.5gm Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
It is not known whether Vaxone S 1.5gm Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
There is limited information available on the use of Vaxone S 1.5gm Injection in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Vaxone S 1.5gm Injection in patients with liver disease. Please consult your doctor.
Uses of Cefoperazone
Cefoperazone is used in the treatment of bacterial infectionsIt is used for short-term treatment of bacterial infections of urinary tract, skin and soft-tissue, ear, bone, blood, abdomen, genital and lungs (pneumonia). It is also used to prevent infections after surgery.
How to use Cefoperazone
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vaxone S 1.5gm Injection works
Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body.
Common Allergic reaction, Nausea, Diarrhoea.
Expert advice for Cefoperazone
Your doctor has prescribed Cefoperazone to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Cefoperazone and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. If you're on blood thinners, Cefoperazone can interact with your medications and increase your bleeding tendencies.
Q. What is cefoperazone sulbactam?
Combination of cefoperazone and sulbactam (beta lactamase inhibitor) are used for the treatment of intra-abdominal infections
Q. Is Cefoperazone nephrotoxic?
No, cefoperazona is not a nephrotoxic drug when given alone, but when given along with aminoglycosides (gentamicin, tobramycin) or other cephalosporins antibiotics, it may increase nephrotoxicity. Please consult your doctor before taking the drug
Q. Is Cefoperazone safe?
Cefoperazone is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Uses of Sulbactam
Sulbactam is used in the treatment of bacterial infections.
How to use Sulbactam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vaxone S 1.5gm Injection works
Sulbactam blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing.
Expert advice for Sulbactam
It is preferentially given as an injection directly into a vein or into a muscle but tablet form is also available.
Tell the doctor if you have diabetes and regularly check your urine for sugar level; ampicillin and sulbactam may cause false positive results.
Do not start or continue the sulbactam and consult your doctor: If you have asthma, runny nose due to allergy (hay fever), or kidney or gastrointestinal disease especially inflammation of large intestine (colitis), If you are pregnant or planning to become pregnant or breastfeeding or become pregnant while taking ampicillin and sulbactam.
Q. Is Sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor
Q. What is Sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins
Q. Is Sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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