Megazid XP 1000 mg/125 mg Injection 
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USED FOR:
Bacterial infections
COMPOSITION:
Ceftazidime (1000mg)
Tazobactum (125mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
PROBABLY SAFE
Megazid XP 1000 mg/125 mg Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
SAFE
Megazid XP 1000 mg/125 mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Megazid XP 1000 mg/125 mg Injection may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
CAUTION
Megazid XP 1000 mg/125 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Megazid XP 1000 mg/125 mg Injection may be needed. Please consult your doctor.
Megazid XP 1000 mg/125 mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Megazid XP 1000 mg/125 mg Injection may be needed. Please consult your doctor.
Uses of Ceftazidime
Ceftazidime is used in the treatment of bacterial infectionsIt is used for short-term treatment of bacterial infections of urinary tract, skin and soft-tissue, ear, bone, blood, abdomen, genital and lungs (pneumonia). It is also used to prevent infections after surgery.
How to use Ceftazidime
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Megazid XP 1000 mg/125 mg Injection works
Ceftazidime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body.
Common Nausea, Diarrhoea, Allergic reaction.
Expert advice for Ceftazidime
Your doctor has prescribed Ceftazidime to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Ceftazidime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. If you're on blood thinners, Ceftazidime can interact with your medications and increase your bleeding tendencies.
Q. Is ceftazidime a sulfa, penicillin or a beta lactam drug?
Ceftazidime does not contain sulfa and is not a penicillin drug. It is beta lactam cephalosporin antibiotic
Q. Is Ceftazidime the same as Rocephin?
No, Rocephin is the brand name for ceftriaxone
Q. Is Ceftazidime dialyzable?
Yes, Ceftazidime is a dialyzable drug
Q. Is ceftazidime and ciprofloxacin compatible?
Yes, ceftazidime and ciprofloxacin are compatible when taken together
Q. What organisms does Ceftazidime cover?
Ceftazidime is active against pseudomonas, anaerobes, and staphylococcus bacteria. It may not be effective against methicillin- resistant Staphylococcus aureus (MRSA).
Q. Is Ceftazidime nephrotoxic?
No, Ceftazidime is not a nephrotoxic drug when given alone but when given along with aminoglycoside antibiotics (gentamicin, tobramycin) or diuretics such as furosemide, it may increase nephrotoxicity.
Uses of Tazobactum
Tazobactum is used in the treatment of bacterial infections.
How to use Tazobactum
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Megazid XP 1000 mg/125 mg Injection works
Tazobactum blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Increased liver enzymes, Bruise, Bleeding, Constipation, Diarrhoea, Altered taste, Shortness of breath, Flatulence, Headache, Insomnia (difficulty in sleeping), Itching, Skin rash, Stomach upset, Vomiting.
Expert advice for Tazobactum
It is given as an infusion (a drip for 30 minutes) into a vein.
Tell the doctor if you have to provide a blood or urine sample for any test because tazobactam and piperacillin may cause false positive results.
Do not start or continue the tazobactam/piperacillin and consult your doctor:
If you are suffering from diarrhea before, or during the treatment with the drug.
If you have kidney or liver problems, low levels of potassium in the blood, or are receiving hemodialysis.
If you develop new or worsening infection, or fits (convulsions) during the treatment.
If you are on a controlled-sodium diet.
If you are pregnant or planning to become pregnant or breastfeeding.
Q. Is tazobactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a beta lactamase Inhibitor
Q. What is tazobactam sodium?
Tazobactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of piperacillin
Q. What is tazact 4.5?
Tazact 4.5 is the brand name for combination of tazobactam and piperacillin
Q. What organisms does tazobactam/piperacillin cover?
Tazobactam in combination with piperacillin is mainly effective against anaerobes and enterococcus, listeria, staphylococcus, citrobacter, haemophilus, moraxella and proteus species but methicillin-resistant staphylococci are resistant to tazobactam/piperacillin
Q. Is tazobactam safe?
Tazobactam is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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