Common Sweating, Headache, Dizziness, Sleepiness, Vomiting, Weakness, Dehydration, Lightheadedness, Dryness in mouth, Nausea, Edema, Fatigue, Anemia, Constipation, Sedation.

Expert advice for Rubuphine Injection
Use Rubuphine as instructed by your doctor. Never take in greater amounts or more often than prescribed. It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery. Avoid consuming alcohol when taking the Rubuphine, as it may cause excessive sleepiness or drowsiness. Inform your doctor if you have ever been diagnosed with kidney or liver problems. Store opioid pain relievers in a safe place and out of reach of others.

Q. Is Rubuphine a narcotic/ controlled substance?
Rubuphine belongs to class of medicines called synthetic opioid analgesics. It is not a narcotic or controlled substance.