Unicristin 1mg Injection 
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NOTICE: unsafe with : Lactation
USED FOR:
Breast cancer
Non-small cell lung cancer
Pancreatic cancer
COMPOSITION:
Vincristine (1mg)
Therapeutic Uses:
anti neoplastics
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Unicristin 1mg Injection is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
UNSAFE
Unicristin 1mg Injection is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Unicristin 1mg Injection may cause side effects which could affect your ability to drive.
CAUTION
Unicristin 1mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Unicristin 1mg Injection may be needed. Please consult your doctor.
CAUTION
Unicristin 1mg Injection should be used with caution in patients with liver disease. Dose adjustment of Unicristin 1mg Injection may be needed. Please consult your doctor.
Uses of Unicristin Injection
Unicristin 1mg Injection is used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.
How to use Unicristin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Unicristin Injection works
Unicristin 1mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Common Hair loss, Peripheral neuropathy (tingling and numbness of feet and hand), Constipation.
Expert advice for Unicristin Injection
Avoid being near people suffering from infections (such as, cold, flu, contagious illnesses), as you may be more susceptible to infections, while on vincristine therapy, because of possibility of leukopenia.Avoid even accidental contamination of eyes with vincristine as it may cause severe irritation.Vincristine may cause acute kidney disease (nephropathy) related to uric acid level.Care should be taken in elderly patients because they are more susceptible to neurotoxic effects of vincristine.In males, vincristine may cause aspermia (lack of semen causing infertility); in females vincristine may cause amenorrhea (absence of menstruation), which may recover after some duration.Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Q. Is Unicristin cardiotoxic/ototoxic?
Unicristin when used in combination with other drugs has shown to be cardiotoxic/ototoxic with unknown cause
Q. Is Unicristin an alkylating agent/ an anthracycline?
Unicristin is vinca alkaloid and not an alkylating agent/ an anthracycline
Q. Is Unicristin a vesicant?
Unicristin is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly
Q. Is Unicristin non DNA binding?
Unicristin does not bind to DNA
Q. Is Unicristin neuropathy reversible?
Unicristin neuropathy is not reversible
Q. Is Unicristin FDA approved?
Unicristin is a FDA approved medication
Q. Is Unicristin cytotoxic?
Unicristin is a cytotoxic drug
Q. Does Unicristin cause hair loss/infertility/ lower blood counts/ neutropenia/ neuropathy/ fever/ nausea?
These side effects are commonly observed with the use of Unicristin drug
Q. How does Unicristin affect mitosis?
Unicristin works by interfering with the growth of cancer cells (mitotic inhibition) and slows their spread in the body by causing an arrest of cell division in metaphase
Q. Where does Unicristin come from?
Unicristin is a plant alkaloid comes from the source called Vinca rosea Linn.
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