Supime 500 mg/250 mg Injection 
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USED FOR:
Bacterial infections
COMPOSITION:
Cefepime (500mg)
Sulbactam (250mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
PROBABLY SAFE
Supime 500 mg/250 mg Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
SAFE
Supime 500 mg/250 mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
It is not known whether Supime 500 mg/250 mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Supime 500 mg/250 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Supime 500 mg/250 mg Injection may be needed. Please consult your doctor.
Supime 500 mg/250 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Supime 500 mg/250 mg Injection may not be needed in these patients. Please consult your doctor.
Uses of Cefepime
Cefepime is used in the treatment of bacterial infectionsIt is used for short-term treatment of bacterial infections of urinary tract, skin and soft-tissue, blood, abdomen, genital and lungs (pneumonia). It is also used to prevent infections after surgery.
How to use Cefepime
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Supime 500 mg/250 mg Injection works
Cefepime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body.
Common Rash, Itching, Nausea, Vomiting, Headache, Fever, Diarrhoea.
Expert advice for Cefepime
Your doctor has prescribed Cefepime to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Cefepime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. If you're on blood thinners, Cefepime can interact with your medications and increase your bleeding tendencies.
Q. Is cefepime beta lactam, penicillin, or sulfa drug?
Cefepime does not contain sulfa and is not a penicillin drug. It is a beta lactam cephalosporin antibiotic
Q. Is Cefepime broad spectrum bacteriostatic or bactericidal?
Cefepime is a broad spectrum bactericidal antibiotic
Q. Is cefepime compatible with lactated ringer's, normal saline, or vancomycin?
Cefepime is compatible with lactated ringer's or normal saline. Solutions of cefepime should not be added to vancomycin. However, if concurrent therapy with cefepime is indicated, vancomycin can be administered separately. Please consult your doctor before taking the drug
Q. Is Cefepime a vesicant?
No, Cefepime is not a vesicant drug
Q. What organisms does Cefepime cover?
Cefepime is mainly effective against methicillin-sensitive Staphylococcus aureus (mssa), gram-negative bacteria, klebsiella, Group B streptococci but not effective against enterococcus, methicillin-resistant Staphylococcus aureus (mrsa), or anaerobes such as mycoplasma.
Uses of Sulbactam
Sulbactam is used in the treatment of bacterial infections.
How to use Sulbactam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Supime 500 mg/250 mg Injection works
Sulbactam blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing.
Expert advice for Sulbactam
It is preferentially given as an injection directly into a vein or into a muscle but tablet form is also available.
Tell the doctor if you have diabetes and regularly check your urine for sugar level; ampicillin and sulbactam may cause false positive results.
Do not start or continue the sulbactam and consult your doctor: If you have asthma, runny nose due to allergy (hay fever), or kidney or gastrointestinal disease especially inflammation of large intestine (colitis), If you are pregnant or planning to become pregnant or breastfeeding or become pregnant while taking ampicillin and sulbactam.
Q. Is Sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor
Q. What is Sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins
Q. Is Sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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