Zontum 4000 mg/500 mg Injection 
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USED FOR:
Bacterial infections
Serious bacterial infections
COMPOSITION:
Piperacillin (4000mg)
Tazobactum (500mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
PROBABLY SAFE
Zontum 4000 mg/500 mg Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
SAFE
Zontum 4000 mg/500 mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
It is not known whether Zontum 4000 mg/500 mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Zontum 4000 mg/500 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Zontum 4000 mg/500 mg Injection may be needed. Please consult your doctor.
Zontum 4000 mg/500 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Zontum 4000 mg/500 mg Injection may not be needed in these patients. Please consult your doctor.
Uses of Piperacillin
Piperacillin is used in the treatment of bacterial infections and serious bacterial infections.
How to use Piperacillin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zontum 4000 mg/500 mg Injection works
Piperacillin is an antibiotic. It kills bacteria by preventing them from forming their own protective covering which is required for their survival in the human body.
Common Nausea, Allergic reaction, Vomiting, Diarrhoea.
Expert advice for Piperacillin
Make sure you complete the course even if you start to feel better. It is better to take with food to avoid an upset stomach. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Discontinue Piperacillin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Q. Is piperacillin related to penicillin?
Yes, piperacillin is a semi-synthetic, extended spectrum penicillin
Q. Is piperacillin compatible with morphine?
Piperacillin is not reported to interact with morphine. Please follow the advice of the doctor regarding their simultaneous use
Q. What is Piperacillin tazobactam?
Piperacillin and tazobactam are used as combination therapy for bacterial infections. Tazobactam reduces the destruction of Piperacillin from chemicals released from bacteria and extends their spectrum of activity
Q. What organisms does Piperacillin cover?
Piperacillin is mainly effective against enterococcus, listeria, and serious gram-negative infections. It does not act against methicillin-resistant staphylococci
Q. Is Piperacillin nephrotoxic?
Piperacillin may be nephrotoxic when taken along with vancomycin or when given to children with cancer or other impairments. Consult and inform your doctor about any medical problems you may have before taking Piperacillin
Q. Is Piperacillin safe?
Piperacillin is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Uses of Tazobactum
Tazobactum is used in the treatment of bacterial infections.
How to use Tazobactum
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zontum 4000 mg/500 mg Injection works
Tazobactum blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Increased liver enzymes, Bruise, Bleeding, Constipation, Diarrhoea, Altered taste, Shortness of breath, Flatulence, Headache, Insomnia (difficulty in sleeping), Itching, Skin rash, Stomach upset, Vomiting.
Expert advice for Tazobactum
It is given as an infusion (a drip for 30 minutes) into a vein.
Tell the doctor if you have to provide a blood or urine sample for any test because tazobactam and piperacillin may cause false positive results.
Do not start or continue the tazobactam/piperacillin and consult your doctor:
If you are suffering from diarrhea before, or during the treatment with the drug.
If you have kidney or liver problems, low levels of potassium in the blood, or are receiving hemodialysis.
If you develop new or worsening infection, or fits (convulsions) during the treatment.
If you are on a controlled-sodium diet.
If you are pregnant or planning to become pregnant or breastfeeding.
Q. Is tazobactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a beta lactamase Inhibitor
Q. What is tazobactam sodium?
Tazobactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of piperacillin
Q. What is tazact 4.5?
Tazact 4.5 is the brand name for combination of tazobactam and piperacillin
Q. What organisms does tazobactam/piperacillin cover?
Tazobactam in combination with piperacillin is mainly effective against anaerobes and enterococcus, listeria, staphylococcus, citrobacter, haemophilus, moraxella and proteus species but methicillin-resistant staphylococci are resistant to tazobactam/piperacillin
Q. Is tazobactam safe?
Tazobactam is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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