Pre OP 500 mg/250 mg Injection 
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USED FOR:
Bacterial infections
COMPOSITION:
Ampicillin (500mg)
Sulbactam (250mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
PROBABLY SAFE
Pre OP 500 mg/250 mg Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
SAFE
Pre OP 500 mg/250 mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
It is not known whether Pre OP 500 mg/250 mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Pre OP 500 mg/250 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pre OP 500 mg/250 mg Injection may be needed. Please consult your doctor.
There is limited information available on the use of Pre OP 500 mg/250 mg Injection in patients with liver disease. Please consult your doctor.
Uses of Ampicillin
Ampicillin is used in the treatment of bacterial infections.
How to use Ampicillin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pre OP 500 mg/250 mg Injection works
Ampicillin is an antibiotic. It kills bacteria by preventing them from forming their own protective covering which is required for their survival in the human body.
Common Rash.
Expert advice for Ampicillin
Make sure you complete the course even if you start to feel better. It is better to take with food to avoid an upset stomach. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Discontinue Ampicillin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Q. Is ampicillin and amoxicillin the same?
Ampicillin and amoxicillin belongs to the same group of penicillin antibiotics, but differ slightly in their uses
Q. Is Ampicillin light-sensitive?
Yes, Ampicillin is light sensitive it should be kept away from sunlight
Q. Does Ampicillin cover anaerobes, listeria?
Ampicillin is used for infections caused by anaerobes and listeria. It is not typically used to treat chlamydia
Q. Is Ampicillin/Megapen a prodrug?
No, Ampicillin is not a prodrug
Q. Is Ampicillin a cephalosporin?
Ampicillin is not a cephalosporin
Q. Can I take Ampicillin for strep throat, tooth infection, sore throat, chlamydial and bacterial vaginitis?
Ampicillin can be used to treat strep throat, tooth infection, sore throat, bacterial vaginitis
Q. Can I take Ampicillin with Advil (ibuprofen), Tylenol (paracetamol) and Benadryl?
Ampicillin can be taken with paracetamol and Benadryl. Ampicillin when taken with ibuprofen may increase the effects of either drug.
Uses of Sulbactam
Sulbactam is used in the treatment of bacterial infections.
How to use Sulbactam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pre OP 500 mg/250 mg Injection works
Sulbactam blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing.
Expert advice for Sulbactam
It is preferentially given as an injection directly into a vein or into a muscle but tablet form is also available.
Tell the doctor if you have diabetes and regularly check your urine for sugar level; ampicillin and sulbactam may cause false positive results.
Do not start or continue the sulbactam and consult your doctor: If you have asthma, runny nose due to allergy (hay fever), or kidney or gastrointestinal disease especially inflammation of large intestine (colitis), If you are pregnant or planning to become pregnant or breastfeeding or become pregnant while taking ampicillin and sulbactam.
Q. Is Sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor
Q. What is Sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins
Q. Is Sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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