Plugpen XP Injection 
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USED FOR:
Serious bacterial infections
Bacterial infections
COMPOSITION:
Meropenem (NA)
Sulbactam (NA)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
PROBABLY SAFE
Plugpen XP Injection is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Plugpen XP Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
It is not known whether Plugpen XP Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Plugpen XP Injection should be used with caution in patients with kidney disease. Dose adjustment of Plugpen XP Injection may be needed. Please consult your doctor.
There is limited information available on the use of Plugpen XP Injection in patients with liver disease. Please consult your doctor.
Uses of Meropenem
Meropenem is used in serious bacterial infectionsIt is used in infections of various body parts like skin and soft tissues, urinary tract, blood, brain and lungs (pneumonia).
How to use Meropenem
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Plugpen XP Injection works
Meropenem is an antibiotic. It kills bacteria by preventing them from forming their own protective covering which is required for their survival in the human body.
Common Nausea, Vomiting, Seizure.
Expert advice for Meropenem
Meropenem is given as an injection directly into a vein by a doctor or nurse using water for injections or a suitable infusion fluid. Do not start or continue the meropenem and consult your doctor:
If you have kidney or liver problems.
If you have a history of seizures or central nervous system problems (e.g. brain lesions).
If you experience severe and persistent diarrhea after taking antibiotics.
If you are taking other drugs like probenecid, valproic acid, or oral anticoagulants like warfarin.
If you are pregnant, planning to become pregnant or breastfeeding.
Q. Is meropenem a penicillin, cephalosporin, or beta lactam drug?
Meropenem is not a penicillin or cephalosporin drug. It is a carbapenem beta-lactam antibiotic
Q. Is Meropenem safe?
Meropenem is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Meropenem dialyzable?
Yes, Meropenem is dialyzable
Q. Is meropenem compatible with vancomycin, or potassium?
Meropenem may be compatible with potassium or vancomycin. Please consult your doctor before taking the drug
Q. Is Meropenem nephrotoxic, vesicant or cause thrombocytopenia?
Meropenem may be nephrotoxic, vesicant, and may cause thrombocytopenia. Please consult your doctor if you experience these side effects
Q. What organisms does Meropenem cover?
Meropenem is active against gram-positive and gram-negative bacteria, aerobes as well as anaerobes. It is effective against enterococcus, streptococcus, and methicillin-sensitive Staphylococcus aureus (MSSA), but not effective against listeria or methicillin-resistant Staphylococcus aureus.
Uses of Sulbactam
Sulbactam is used in the treatment of bacterial infections.
How to use Sulbactam
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Plugpen XP Injection works
Sulbactam blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.
Common Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing.
Expert advice for Sulbactam
It is preferentially given as an injection directly into a vein or into a muscle but tablet form is also available.
Tell the doctor if you have diabetes and regularly check your urine for sugar level; ampicillin and sulbactam may cause false positive results.
Do not start or continue the sulbactam and consult your doctor: If you have asthma, runny nose due to allergy (hay fever), or kidney or gastrointestinal disease especially inflammation of large intestine (colitis), If you are pregnant or planning to become pregnant or breastfeeding or become pregnant while taking ampicillin and sulbactam.
Q. Is Sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor
Q. What is Sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins
Q. Is Sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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