Side Effects:

Common Allergic reaction.

Expert advice for Perfalgan Infusion
Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action. Starts working within one hour. Wait for at least 4 hours before taking the next dose. Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems. Discontinue Perfalgan and inform your doctor immediately if rash occurs. For children, measure the doses of liquid Perfalgan using the measuring cup instead of a teaspoon to avoid under or over-dosage. Avoid excess alcohol intake (>3 glasses/day) when taking Perfalgan as it may cause liver damage.

Frequently Asked Questions

Q. Can I take Perfalgan with vitamin B complex?
Yes, Perfalgan can be taken with vitamin B-complex preparations. They have been used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Perfalgan helps to relieve pain and vitamin B-complex corrects the deficiency that might be causing your symptoms.

Q. Is Perfalgan use associated with Helicobacter pylori infection?
No, Perfalgan use is not associated with Helicobacter pylori infection. Painkiller drugs can increase the acid secretion in the stomach, aggravate the symptoms of this infection and the risk of stomach and the intestine ulcer. However, this risk is minimum with Perfalgan as compared to other pain killers.

Q. Can I take Perfalgan with fexofenadine?
Yes, Perfalgan can be taken safely with fexofenadine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore-throat and other allergic or viral diseases. Fexofenadine helps to relieve sneezing, runny nose, itchy throat, or eyes and Perfalgan helps to relieve pain or fever.

Q. Can I take Perfalgan with warfarin?
Perfalgan is safe to use occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Perfalgan can also increase the risk of bleeding. Talk to your doctor before taking them together as you may need to be monitored regularly.

Q. Can I take Perfalgan with tamsulosin?
Perfalgan can be taken with Tamsulosin. No harmful side effects or other interactions have been seen when they are taken together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.

Q. Can I take Perfalgan with cetirizine?
Yes, Perfalgan can be taken safely with cetirizine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat, or eyes and Perfalgan helps to relieve pain or fever.

Q. Can I take Perfalgan with ibuprofen?
Yes, Perfalgan can be taken with ibuprofen. Both help to relieve pain and fever and ibuprofen also decreases inflammation and swelling. However, both increase the acid secretion in the stomach and can cause acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.

Q. Does Perfalgan cause weight loss?
Perfalgan is not known to cause weight loss. It is a very safe medicine for short term use and can cause minor and rare side effects like low blood pressure, and allergic reactions.

Q. Can anyone be allergic to Perfalgan?
Yes, there have been reports of hypersensitivity and allergic reaction with the use of Perfalgan. Symptoms of an allergy include swelling of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop taking Perfalgan if you have such symptoms and immediately consult your doctor.

Q. How beneficial is to use Perfalgan with diclofenac?
Perfalgan and Diclofenac might be given together in case of fever and pain. Perfalgan has an early onset of action and it helps in relieving the symptoms till diclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.

Q. Can I take Perfalgan for stomach pain?
No, Perfalgan should not be taken for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying condition, which needs attention.

Q. Can I take Perfalgan with aceclofenac?
Yes, Perfalgan can be given with aceclofenac for fever and pain. Perfalgan has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.

Q. Does Perfalgan treat sore-throat, flu or cold?
Perfalgan does not treat sore-throat, flu or cold but it can help in relieving fever and body aches associated with these conditions.

Q. Can I take Perfalgan with codeine?
Perfalgan and codeine can be taken together. No drug-drug interactions or any harmful effects have been reported when they are used together. They are commonly given together for the relief of mild to moderate pain due to different reasons.

Q. Does Perfalgan help a cough?
No, Perfalgan does not help in the relief of cough but it can help in relieving associated fever and body aches.

Q. Does Perfalgan contain alcohol?
No, Perfalgan does not contain any alcohol.

Q. Can I take Perfalgan with amoxicillin?
Perfalgan and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Perfalgan is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Does Perfalgan have side effects?
Perfalgan is quite safe for short term use. It has side effects if taken in more than the dose advised and for a long-term. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of Perfalgan.

Q. Is Perfalgan safe to use?
Perfalgan is safe to use in the dose as advised by the doctor. Use in more than recommended doses can do serious harm.

Q. Is it safe to take Perfalgan with erythromycin?
Perfalgan and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Perfalgan is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Is Perfalgan an antibiotic?
Perfalgan is not an antibiotic. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is useful for the treatment of infections.

Q. Can I take Perfalgan with metronidazole?
Perfalgan and Metronidazole can be taken together. No drug-drug interactions or any harmful effects have been reported when used together.

Q. Can I take Perfalgan with homeopathic medicine?
Ask your doctor before taking Perfalgan with homeopathic medicine as there is no information available on this.

Q. Is it safe to take Perfalgan with Tramadol?
Yes, Perfalgan can be taken with Tramadol. They are used together for moderate to severe pain in various diseases and their use is associated with common side effects like nausea, dizziness, and sleepiness.No drug-drug interactions have been reported when they are used together.

Q. Can I take Perfalgan with Azithromycin?
Perfalgan and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Perfalgan is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Is it safe to take Perfalgan with Naproxen?
Yes, Perfalgan can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are used to relieve pain and fever. However, long-term use affects the stomach lining and increase acid secretion which can lead to side effects like acid reflux, heartburn, stomach, and intestinal ulcers and bleeding.

Q. Can a patient with high blood pressure take Perfalgan?
Occasional use of Perfalgan is safe in patients with high blood pressure. However, if it is to be taken for a long time, you must talk to your doctor. Perfalgan belongs to the group of painkillers called analgesics and antipyretics and these drugs can decrease the action of medicines taken by the patient for control of high blood pressure.

Q. Does Perfalgan interact with vitamin C?
Vitamin C can be taken with Perfalgan. However, vitamin C increases the blood levels of other drugs similar to Perfalgan, so it is advised to talk to your doctor if you have to take both these medicines for a long-term.

Q. What happens if you take an overdose of Perfalgan?
Overdose of Perfalgan can cause potentially life-threatening liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage, decreased platelet count and coma may also occur. Immediately consult a doctor or consult an emergency in the case of suspected overdosage.

Q. Can I take Perfalgan with hyoscine?
Yes, Perfalgan and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Perfalgan is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.

Q. Can I take Perfalgan with Betahistine?
Perfalgan can be taken with Betahistine. There are no reported drug-drug interactions or harmful effects when they are used together.

Q. Can I take Perfalgan with rabeprazole?
Perfalgan and Rabeprazole can be taken together. Rabeprazole is used to prevent Perfalgan (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.

Q. How beneficial is to take urofollitropin alpha with Perfalgan?
Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Perfalgan.

Q. Can vitamin D be taken safely with Perfalgan?
Yes, vitamin D can be taken with Perfalgan. Patients with osteoarthritis who are on vitamin D and calcium may need to take Perfalgan for the relief of any associated pain. No drug-drug interactions or any harmful effects have been reported.

Q. Can I take clindamycin with Perfalgan?
Perfalgan and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Perfalgan may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.

Q. Does Perfalgan affect the liver?
Use of Perfalgan for a long time and above recommended doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Perfalgan from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.

Q. Can I take Perfalgan if I have hepatitis?
Perfalgan is considered the safest painkiller to take for people with hepatitis for mild to moderate pain and fever. However, Perfalgan is metabolized in the liver, so, consult your doctor before taking Perfalgan if you have hepatitis as it can cause liver damage if taken in higher doses or for a very long time.

Q. What are the serious side effects of taking excess Perfalgan?
Potentially severe life-threatening liver injury is a serious side effect seen with an overdose of Perfalgan. Overdose can also cause kidney injury, coma, and decreased platelet count. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of suspected overdose.