USED FOR:
Serious bacterial infections
COMPOSITION:
Imipenem (250mg)
Cilastatin (250mg)
Therapeutic Uses:
anti infectives
Interaction with alcohol is unknown. Please consult your doctor.
Primapen 250 mg/250 mg Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Primapen 250 mg/250 mg Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Do not drive unless you are feeling well.There are some side effects associated with this medicine (such as seeing, hearing, or feeling something that is not there) that may affect some patients' ability to drive.
Primapen 250 mg/250 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Primapen 250 mg/250 mg Injection may be needed. Please consult your doctor.
There is limited information available on the use of Primapen 250 mg/250 mg Injection in patients with liver disease. Please consult your doctor.
Uses of Imipenem
Imipenem is used in serious bacterial infectionsIt is used in infections of various body parts like skin and soft tissues, urinary tract, blood, brain and lungs (pneumonia).
How to use Imipenem
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Primapen 250 mg/250 mg Injection works
Imipenem is an antibiotic. It kills bacteria by preventing them from forming their own protective covering which is required for their survival in the human body.
Common Nausea, Vomiting, Seizure.
Expert advice for Imipenem
Imipenem is given as a powder for solution for intravenous infusion by a doctor or nurse using a suitable infusion fluid.
Do not start or continue the imipenem, if you have kidney, liver, or urinary problems; history of fits (seizures) or central nervous system problems (e.g. tremors).
Do not take imipenem if you experience inflammation of the large intestine (colitis) or any other gastrointestinal disease.
Do not drive or operate heavy machinery because you may feel sleepy or dizzy while being treated with imipenem.
Avoid using imipenem, if you are pregnant, planning to become pregnant or breastfeeding.
Q. Is imipenem a penicillin or beta lactam drug?
Imipenem is not a penicillin drug. It is a carbapenem beta-lactam antibiotic
Q. Is Imipenem nephrotoxic or cause seizures?
Ganciclovir along with Imipenem can increase risk of seizures. Imipenem generally not been shown to cause nephrotoxicity. Please consult your doctor if you experience these side effects
Q. What is imipenem-cilastatin used for?
Imipenem and cilastatin are used as combination therapy for bacterial infections. Cilastatin reduces the inactivation of imipenem from enzymes released from kidney and extends their spectrum of activity
Q. What organisms does Imipenem cover?
Imipenem is active against most of the gram-positive and gram-negative bacteria, aerobes as well as anaerobes. It is effective against pseudomonas, legionella, and acinetobacter, and many other; not treatable by other antibiotics.
Uses of Cilastatin
Cilastatin is used in the treatment of serious bacterial infections.
How to use Cilastatin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Primapen 250 mg/250 mg Injection works
Cilastatin blocks the enzymes that destroys other antibiotics.
Common Vomiting, Nausea, Allergic reaction, Confusion, Diarrhoea, Fever, Rash.
Expert advice for Cilastatin
You will be monitored for kidney and liver function due to the risk of toxicity.
Tell your doctor if you are on a controlled sodium diet, as cilastatin contains sodium.
Tell your doctor if you are pregnant or are planning to be pregnant or are breastfeeding.
Tell your doctor if you have or have ever had seizures; a brain injury; kidney, liver, or gastrointestinal disease (especially colitis); or asthma.
Do not take if patient is allergic to cilastatin or any of its ingredients.
Do not take children less than 1 year, and child with a brain or nervous system infection, or weighs less than 66 lb (30 kg) and has kidney problems
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