Side Effects:

Common Nausea, Headache, Diarrhoea, Fatigue.

Expert advice for Jolivel Tablet
It can take 2-3 weeks for Jolivel to start working. Do not stop treatment suddenly as this may cause a stomach upset, flu-like withdrawal symptoms and sleep disturbance. If your doctor asks you to stop Jolivel, you should reduce the dose slowly over 4 weeks. Avoid consuming alcohol when taking the Jolivel, as it may cause excessive drowsiness and calmness. The addiction/dependence potential of Jolivel is very less. You may develop anxiety during initiation of therapy.

Frequently Asked Questions

Q. How does Jolivel work?
Jolivel works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.

Q. Can I take Jolivel with coffee?
There is usually no significant effect of taking coffee with Jolivel but a very high quantity of consumption of coffee may cause restlessness and anxiety.

Q. Is Jolivel addictive?
No. Jolivel is not addictive. Its abrupt discontinuation may cause some withdrawal symptoms. But still is not addictive as there is no drug-seeking behaviour and it has no abuse liability.

Q. Why does Jolivel cause nausea?
Jolivel increases the activity of serotonin a chemical which is also involved in the vomiting process so makes the person nauseating.

Q. Why does Jolivel make me tired?
Tiredness is usually associated with depression. Jolivel can alter the sleep quality and can make the person feel tired most of the time.

Q. Can I use Jolivel for a migraine?
Jolivel is not approved for the treatment of a migraine. It is used in the treatment of depression, anxiety disorder, phobia, post-traumatic stress disorder and obsessive-compulsive disorder.

Q. Can I use Jolivel for bipolar disorder?
Jolivel should not be used for the treatment of bipolar disorder as it can aggravate the problem. Only in few cases, it can be used that too with caution with other drugs if depression is the more persistent feature of person's bipolar illness. But the person should be very regular with drugs prescribed for the mania part also called mood stabilisers.

Q. Does Jolivel cause hair loss?
There are some case reports of hair loss with the use of Jolivel. It is very infrequent and it usually stops after the discontinuation of the drug. It can be very distressing for a person, especially for the females. So a person should tell his doctor if he is having hair loss with the use of Jolivel.

Q. Can I use Jolivel for sleep problem?
Jolivel may itself cause sleep disorders. So it is not recommended for the sleep problem.

Q. Can I use Jolivel for obsessive-compulsive disorder (OCD)?
Jolivel can be used for the treatment of obsessive-compulsive disorder (OCD) but there are better alternatives available, in case they don't work then Jolivel can be used. Although it is prescribed in a higher dose and for longer duration in case of OCD in comparison to depression.

Q. Which is better medication, Jolivel or sertraline?
Jolivel is the safest drug in its class. Sertraline can be used in case Jolivel doesn't work for depression. However, setraline can be preferred in case of obsessive-compulsive disorder (OCD).

Q. Which is better medication, Jolivel or citalopram?
Jolivel is more effective than citalopram for major depression. Although some studies have shown that there is no difference among two in case of effectiveness but some recent studies have shown Jolivel to be superior to citalopram for major depression.

Q. Can I take Jolivel with diphenhydramine?
It is better to avoid diphenhydramine with Jolivel. Diphenhydramine can aggravate side effects of Jolivel and can cause dizziness, confusion and difficulty in concentrating.

Q. Can I take Jolivel with aspirin?
It is usually avoided as it can increase the chances of bleeding.

Q. Can I take Jolivel with Ibuprofen?
No. Combined these two drugs may increase the chances of bleeding especially in persons already on a blood thinner. Nasal bleeding is usually the first symptom.

Q. Can I take Jolivel with methylphenidate?
It is better to avoid methylphenidate with Jolivel. Because methylphenidate can increase the blood levels of Jolivel and its effects and rarely can cause a serious condition called serotonin syndrome with symptoms like anxiety, restlessness, extreme changes in heart rate and blood pressure, blurred vision, incoordination, nausea, vomiting, diarrhoea.

Q. Can Jolivel be given with lisdexamfetamine?
It is better to avoid this combined therapy of lisdexamfetamine with Jolivel, it leads to increased anxiety, restlessness and sometimes serotonin syndrome. Serotonin syndrome includes vomiting, diarrhoea, extreme changes in blood pressure and even seizure may occur. It can be life-threatening.

Q. Can I take Jolivel with alprazolam?
It is better to avoid the combination, it can lead to increased dizziness, confusion and difficulty in concentrating. Please consult your doctor before taking these two medicines together.

Q. Can I take Jolivel with clonazepam?
It is better to avoid the combination, it can lead to increased dizziness, confusion and difficulty in concentrating. Please consult your doctor before taking these two medicines together.

Q. Can Jolivel be used with hydrocodone?
It is better to avoid the combination, it can lead to increased dizziness, confusion and difficulty in concentrating. Please consult your doctor before taking these two medicines together.

Q. Can I take Jolivel with dextromethorphan?
You should not take Dextromethorphan with Jolivel. It can lead to the seotonin syndrome. Before taking any medications with Jolivel, your should consult with your doctor.

Q. Can I take Jolivel and paracetamol?
Yes. There is no known interaction between Jolivel and paracetamol.

Q. How does Jolivel differ from fluoxetine?
Jolivel and fluoxetin belongs to same class of medicine called as selective serotonin reuptake inhibitor (SSRI).

Q. How doses Jolivel differ from amitriptyline?
Jolivel is a newer drug belongs to class selective serotonin reuptake inhibitor (SSRI) while amitryptiline is an older drug belonging to class tricyclic antidepressants (TCA). Both drugs are almost equally effective for treating depression but Jolivel has much lesser side effects in comparison to amitryptiline and so preferred over amitryptiline for the treatment of depression.

Q. How does Jolivel differ from imipramine?
Jolivel is much safer than imipramine and is preferred in most of the conditions over imipramine. However, imipramine can be preferred in bed-wetting in children.

Q. What would happen if I stop taking Jolivel?
You may experience withdrawal symptoms which can be in the form flu like symptoms, anxiety, suicidal thoughts, nausea or sleep problems. These symptoms usually last for one to two weeks. Do not stop taking this medicine without consulting your doctor.

Q. When and How to stop Jolivel?
You should consult your doctor before stopping the treatment. It would depend on the number and severity of depressive episodes.The dose should be tapered slowly to prevent intense withdrawal symptoms.

Q. Is Jolivel a benzodiazepine?
No. Jolivel is not a benzodiazepine. Benzodiazepines decrease the anxiety and induce sleep. Jolivel belongs to the class of selective sertonin reuptake inhibitor (SSRI). It may cause insomnia and restlessness initially as the side effect which usually goes away with time.

Q. Is Jolivel a narcotic?
No. Jolivel is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.