Reliseal Kit 
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USED FOR:
Bleeding
COMPOSITION:
Aprotinin (3000KIU/ml)
Fibrinogen (70mg)
Thrombin (500IU)
Therapeutic Uses:
blood related
cardiac
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Reliseal Kit may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of Reliseal Kit during lactation. Please consult your doctor.
Not relevant, as Reliseal Kit is intended for use in hospitalised patients.
Reliseal Kit is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Reliseal Kit may not be needed in these patients. Please consult your doctor.
CAUTION
Reliseal Kit should be used with caution in patients with liver disease. Dose adjustment of Reliseal Kit may be needed. Please consult your doctor.
Uses of Aprotinin
Aprotinin is used in the treatment of bleedingIt is used to prevent or reduce bleeding for short period of time in conditions like heavy periods, dysfunctional uterine bleeding, nosebleed, tooth removal, after prostate surgery or after bladder surgery.
How to use Aprotinin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Reliseal Kit works
Aprotinin prevents the breakdown of clots and stops bleeding.
Common Nausea, Vomiting, Diarrhoea.
Expert advice for Aprotinin
Before you start with aprotinin treatment you may need to take a test dose to make sure that you do not develop allergic reactions.Ensure that the medication is not sprayed from a close distance to the wound and should not be injected in blood vessels.You may be monitored with lab test, including kidney function test and clotting test while on aprotinin treatment.Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Uses of Fibrinogen
Fibrinogen is used in the treatment of bleeding.
How to use Fibrinogen
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Reliseal Kit works
Fibrinogen is a chemical messenger which fastens the process of clot formation and stops bleeding.
Common Irritation of ear, Allergic skin rash, Decreased blood pressure, Shortness of breath, Fever.
Expert advice for Fibrinogen
Inform your doctor if you have had a heart attack or a history of poor blood supply to heart (coronary heart disease) or if you are suffering from liver disease.
Tell your doctor about any recent or planned surgery.
Seek immediate medical attention if your experience sudden skin reactions, difficulty in breathing, fall in blood pressure or dizziness.
Inform your doctor if you have a condition that make you more prone to blood clots than normal (thromboembolic disorders).
Strict medical supervision should be ensured while treating newborns with fibrinogen.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Do not take if allergic to fibrinogen or any of its ingredients.
Q. Does Fibrinogen activate platelets?
Yes. Fibrinogen activates platelets to participate in the clotting process and form a stable plug that blocks and stops excessive bleeding
Q. Is Fibrinogen an insoluble plasma protein?
No, Fibrinogen is a soluble plasma glycoprotein
Q. Is it found in serum?
No. Fibrinogen is found in blood plasma and not serum
Q. Is Fibrinogen a formed element in blood?
It is formed in the liver and found in blood when there is rupture and bleeding within blood vessels to bring about clotting or coagulation.
Uses of Thrombin
Thrombin is used in the treatment of bleeding.
How to use Thrombin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Reliseal Kit works
Thrombin is a chemical that fastens the process of clot formation and stops bleeding.
Common Arterial thromboembolism (blood clot in artery), Reduced blood platelets, Arterial hypotension (low blood pressure), Fever, Anemia, Increased heart rate, Postoperative wound infection, Bleeding, Hypersensitivity.
Expert advice for Thrombin
Exercise caution if you are an elderly patient.Â
Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
Do not take if you are allergic to thrombin or any of its ingredients.
Do not take if you have severe reactions to human blood products.
Do not give to patients with severe or brisk bleeding from the arteries.
Q. Is Thrombin a plasma protein or an enzyme?
Thrombin is an enzyme that converts fibrinogen to fibrin to form fibrin clot.
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