Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.

Spikool LS 75mg/20mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

No information is available on the use of Spikool LS 75mg/20mg Tablet during lactation. Please consult your doctor.

Do not drive unless you are feeling well.Spikool LS 75mg/20mg Tablet may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.

There is limited information available on the use of Spikool LS 75mg/20mg Tablet in patients with kidney disease. Please consult your doctor.However, limited data suggest a cautious use of this medicine in these patients.

Spikool LS 75mg/20mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Spikool LS 75mg/20mg Tablet may be needed. Please consult your doctor.