Side Effects:

Common Gastrointestinal irritation, Nausea, Vomiting, Dyspepsia, Gastritis, Bleeding disorder, Reduced blood platelets, Gastric erosion, Gastric ulcer.

Expert advice for Loprin Tablet
Helps prevent future heart attack and clot-related (ischemic) stroke with minimum side effects. Take with food to avoid the risk of bleeding in the stomach or intestines. Notify your doctor if you notice black stools or cough up blood (however small the amount). Discontinue Loprin right away and notify your doctor if you have ringing in your ears, abnormal bleeding, or nausea or vomiting that doesn't go away. Do not use Loprin for fever in children

Frequently Asked Questions

Q. Is Loprin a blood thinner?
Yes, Loprin acts as a blood thinner. In low doses, it has antiplatelet action and it prevents the platelets from sticking together. This helps to decrease the risk of blood clot formation in blood vessels and provides protection from heart attack and stroke.

Q. Is Loprin an NSAID (non-steroidal anti-inflammatory drug)?
Yes, Loprin is a NSAID (non-steroidal anti-inflammatory drug). In low doses, it protects the heart and prevents heart attacks and stroke. In higher doses, it relieves mild to moderate pain, fever, and inflammation and is useful in arthritis, minor body aches, and pains and headache.

Q. Can I take Loprin and clopidogrel together?
Yes, you can take Loprin and clopidogrel together. Fixed-dose combinations of clopidogrel and Loprin are available and effectively lowers the risk of heart attack and is used in patients after a coronary artery stent but it can increase the risk of bleeding.

Q. Is Loprin good for a hangover headache?
No, Loprin should not be used for alcohol hangover/ hangover headache. Alcohol use cause damage to the stomach lining and use of aspirin along with can increase the risk of stomach bleeding.

Q. Is Loprin beneficial in certain diseases of heart?
Yes, at low dose, Loprin is beneficial for patients who are at an increased risk of heart attack and stroke. It is also advised after stent placement or coronary artery bypass. In low doses, it does not allow the platelets to stick together and decreases the risk of blood clot formation.

Q. Can I take Loprin empty stomach?
Yes, Loprin can be taken in an empty stomach particularly to increase its rate and extent of absorption, as the presence of food interferes with Loprin absorption. Having said so, aspirin taken in an empty stomach can irritate the stomach surface and cause erosions.

Q. Is Loprin good for hair growth?
No, Loprin is not known to play any role in hair growth. It is a NSAID (non-steroidal anti-inflammatory drug). In low doses, it protects the heart and prevents heart attacks and stroke. In higher doses, it relieves mild to moderate pain, fever, and inflammation

Q. Is Loprin safe?
Loprin is safe to use in the doses as advised by the doctor, however, there are some common side effects associated with its use like nausea, vomiting, dyspepsia, gastritis, bleeding disorder, decreased blood platelets, gastric erosion, and gastric ulcer.

Q. Can I take Loprin with Tamsulosin?
Loprin and Tamsulosin can be taken together. There are no known drug-drug interactions when they are used together.

Q. Can I take Loprin with famotidine?
Loprin can be taken with famotidine. Loprin is a pain killer and belongs to the group of NSAIDs (non-steroidal anti-inflammatory agents) which can increase the gastric acid secretion and worsen stomach acidity, heartburn, and stomach ulcers and drugs like Famotidine are used to prevent and treat gastric problems caused by painkillers.

Q. Can I take fexofenadine with Loprin?
Yes, you can take fexofenadine with Loprin. Fexofenadine is an anti-histaminic drug used for the treatment of allergic diseases and Loprin is a NSAID (non-steroidal inflammatory drug) and has antiplatelet action and helps to relieve pain, fever, and swelling. There are no reported drug interactions or harmful effects when they are used together.

Q. Are Loprin and ASA (acetylsalicylic acid) the same?
Yes, Loprin and ASA (acetylsalicylic acid) are the names for the same medicine. Aspirin is called acetylsalicylic acid, as it is an acetyl derivative of the salicylic acid and is commonly abbreviated as ASA.

Q. Does Loprin cause H. pylori infection?
Loprin is not known to cause Helicobacter Pylori infection. However, its use in patients already having H. pylori infection can cause an increased risk of stomach ulcers and bleeding due to these ulcers.

Q. Can I take ibuprofen after Loprin?
It is advisable to not take ibuprofen with Loprin. Your doctor can suggest an alternative. Ibuprofen can decrease the antiplatelet effect of Loprin. When taken together, they can cause increased anticoagulation and potassium levels. Also, Loprin can increase the level of ibuprofen. If needed, take ibuprofen 8 hours before Loprin or 2 to 4 hours after.

Q. How and where is Loprin metabolized?
After oral intake, Loprin rapidly gets converted to salicylic acid, its major active circulating form. Both are primarily metabolized (broken down) in the liver to salicyluric acid and products like phenolic and acyl glucuronides and others. All metabolites are excreted through the kidneys.

Q. Why is Loprin contraindicated in patients with asthma?
Yes, use of Loprin is contraindicated in patients with asthma, rhinitis and nasal polyps. Loprin can cause allergic reactions like urticaria (raised, itchy, skin rashes), angioedema (swelling of skin and tissue under the skin), or bronchospasm (narrowing of the airway).

Q. Is there any interaction between Loprin and vitamin D?
No, drug-drug interactions or additional harmful effects have been reported when Loprin and vitamin D are used together.

Q. Is asacol also Loprin?
No, asacol is not Loprin. Asacol is 5-aminosalicylic acid and is used in the treatment of ulcerative colitis while Loprin is acetylsalicylic acid (ASA) and belongs to the group of pain killers.

Q. What are the allergic reactions to Loprin?
Allergic reactions to Loprin can predominantly affect the respiratory airway tract causing nasal congestion, running nose and difficulty in breathing or the allergic reactions can be limited resulting in urticaria (raised, itchy, skin rashes) and angioedema (swelling of the lower layer of skin and tissue just under the skin).

Q. How is Loprin helpful to prevent stroke?
Loprin helps in stopping the processes of platelet adhesion and aggregation (clumping of platelets). Thereby, the risk of formation of blood clots in the vessels supplying the brain is reduced leading to lesser chances of occurrences of stroke.

Q. Is Loprin bad for your liver?
No, as such Loprin does not harm your liver. However, if you already have some liver disorder or haven taken Loprin at high doses, there can be occurrence Loprin-related toxicity. Hence, it is necessary to disclose your liver condition to the treating physician.

Q. How does Loprin act as an antiplatelet drug?
Loprin blocks the enzyme cyclooxygenase which is necessary for the production of thromboxane. Thromboxane normally acts as a pro-aggregatory agent causing the platelets to clump and form a clot. Hence, Loprin by blocking the action of thromboxane functions as an antiplatelet drug.

Q. Can Loprin make one constipated?
Yes, long-term use of Loprin has been associated with constipation. However, occurrence of this side effect is not very common.

Q. Does Loprin really work for acne?
Loprin contains acetyl salicylic acid. And salicylic acid is a common component of most of the topical (local application) creams of acne. However, Loprin as such is not used in the management of acne.