Zefretol 400mg Tablet may cause excessive drowsiness and calmness with alcohol.

Zefretol 400mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Zefretol 400mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.Zefretol 400mg Tablet should be used for short periods and sleepiness of the baby should be watched.

Zefretol 400mg Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.

Zefretol 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zefretol 400mg Tablet may be needed. Please consult your doctor.Use of Zefretol 400mg Tablet is not recommended in patients with severe kidney disease.

Zefretol 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Zefretol 400mg Tablet may be needed. Please consult your doctor.Limited information is available on the use of Zefretol 400mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.