Side Effects:

Common Anxiety, Vomiting, Diarrhoea, Palpitations, Nervousness, Weight loss, Tremor.

Expert advice for Thyrofit Tablet
Your doctor has prescribed Thyrofit to replace the natural thyroid hormone that your own thyroid gland can no longer make. It is best to take Thyrofit on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine. Though it starts working within 1 to 2 weeks, you may have to wait for 6 to 8 weeks to get the full effect. For most people, Thyrofit is a lifelong medication. Do not discontinue it without first discussing with your doctor. Inform your doctor if you have diarrhoea, nervousness, irritability, feeling of a heartbeat, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose. Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine. Get your thyroid hormone and TSH levels checked regularly. Inform your doctor before changing the brand of Thyrofit as all brands may not have the same effect.

Frequently Asked Questions

Q. Can I take Thyrofit during pregnancy?
Thyroid hormone is naturally present in the body and is therefore safe to take in pregnancy. In fact, it is very important that pregnant women or those planning to become pregnant have normal thyroid hormone levels to provide a suitable environment for the baby. If you are already taking thyroid hormone, your dose may need to be increased during pregnancy. Hence, you may have to get your thyroid hormone and TSH levels measured once you know that you are pregnant. You should discuss the timing of thyroid blood tests with your doctor, but often thyroid tests are done every trimester.

Q. Does Thyrofit interact with any other medications?
Use of medications such as birth control pills, estrogen, testosterone, some medications for seizures, depression, and cholesterol, and supplements such as iron and calcium may require you to alter the dose of Thyrofit. It is therefore important that you let your doctor know about all the medications or supplements you are taking.

Q. What is the dose for Thyrofit?
The dose is individualised on the basis of clinical response and biochemical tests. Regular monitoring of thyroid stimulating hormone (TSH) and Thyrofit is recommended when starting therapy or changing the dose. Do not change the dose or stop the medicine without consulting your doctor.

Q. Can I take Thyrofit with tea/coffee/food?
It is best to take Thyrofit on an empty stomach (ideally, first thing in the morning). No tea/coffee, food or milk should be taken 1 hour before and 2 hours after taking this medicine as it affects its absorption.

Q. What happens if we consume too much iodine?
In some people, increased dietary iodine intake causes the thyroid gland to make excess of thyroid hormone, leading to a condition called iodine-induced hyperthyroidism. Too much of iodine can also cause thyroid underactivity, called hypothyroidism as excess iodine blocks the thyroid's ability to produce the hormone.

Q. Is Thyrofit a beta blocker?
No. Thyrofit is not a beta-blocker. It is a hormone synthesised by the thyroid gland present in the neck region. It maintains normal growth & development, body temperature & energy levels.

Q. Is Thyrofit a blood thinner?
No. Thyrofit is not a blood thinner. It is a hormone used for the treatment of hypothyroidism (decreased thyroid hormone). Blood thinners are medicines which prevent abnormal clot formation.

Q. Does Thyrofit cause weight loss?
Yes. Thyrofit can produce side effect as weight loss. It is usually due to excessive dose. However, it should not be used for treat obesity.

Q. Is Thyrofit a growth hormone?
No, Thyrofit is not a growth hormone. It is a hormone synthesized by the thyroid gland present in the neck region. Growth Hormone, on the other hand, is secreted by the pituitary gland present in the brain. Thyrofit is required for the proper functioning of growth hormone.

Q. Is Thyrofit a neurotransmitter?
No, Thyrofit is not a neurotransmitter. Thyrofit is a hormone secreted directly into the blood by the thyroid gland. The blood then takes it to the target organs in the body. A neurotransmitter, on the other hand, transmits impulses from one nerve cell to the other in the brain.

Q. Is Thyrofit a tropic hormone?
Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the pituitary gland in the brain. The thyroid gland secretes Thyrofit, which targets the hypothalamus and therefore can be considered a tropic hormone.

Q. Is Thyrofit a protein?
No. Thyrofit is not a protein. The normal thyroid gland secretes two thyroid hormones - triiodothyronine (T3) and tetraiodothyronine (T4 or Thyrofit). More than 99% of these hormone circulating in the blood as bound to carrier proteins, Thyrofit-binding globulin, synthesised in the liver.

Q. Is Thyrofit a peptide or steroid?
Thyrofit is neither a peptide nor a steroid. Thyrofit is an amino acid (tyrosine) derived hormone. (Amino acids are tiny building blocks of proteins, but they cannot be called proteins by themselves unless a number of them are connected in a sequence).

Q. Can Thyrofit be used as hormone replacement therapy?
Yes. Thyrofit can be used as a hormone replacement therapy to compensate the deficiency of thyroid hormone in the body.

Q. Is Thyrofit a hormone?
Yes. Thyrofit is a hormone secreted from the thyroid gland. It causes increased oxygen consumption by most tissues of the body, increases the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins.

Q. Is Thyrofit a slowly acting drug?
Yes. Thyrofit is a slow-acting drug. It acts through receptors situated in the nucleus of a cell and results in the formation of various protein to target its action hence Thyrofit takes some time to act.

Q. Is Thyrofit a diuretic?
No. Thyrofit is not a diuretic. It is a hormone secreted by the thyroid gland.

Q. What is Thyrofit poisoning?
Thyrofit poisoning occur if an excessive dose is taken. It present as a headache, hyperactivity, nervousness, anxiety, irritability, heat intolerance, fever, excessive sweating, palpitations, tachycardia, arrhythmias, increased pulse and blood pressure. Inform your doctor as soon as possible.

Q. How Thyrofit modulates erythropoiesis?
Thyrofit is required for the normal functioning of the body. Research has shown that thyroid hormone significantly affects the erythropoiesis and increases red blood cell synthesis. Thyrofit is not approved to treat anemia (decreased red cell count).

Q. In which condition does Thyrofit is used along with carbimazole?
Thyrofit is used with carbimazole in the treatment of Graves disease or hyperthyroidism. Studies have shown it is used as block–replace regimen which means the option of maintaining the high dose of antithyroid drugs along with adding levothyroxine to maintain normal thyroid state.

Q. Can I take an antidepressant along with Thyrofit?
No. There are noted interactions between Thyrofit and few antidepressants which lead to increased adverse effects of both the drugs so consult your doctor and do inform him before prescribing any of the medication.

Q. What is the effect of grapefruit juice on the absorption of Thyrofit?
Grapefruit juice slightly decreases the absorption of levothyroxine when taken together otherwise there is no major interaction between these two.

Q. Can I take vitamins with Thyrofit and what would be its effects?
Yes. Vitamins can be added to your diet and can be taken with Thyrofit, but you should not take vitamin supplement within four hours of taking your thyroid medication.

Q. Can I take omeprazole along with Thyrofit?
No. Omeprazole should not be taken with Thyrofit. Omeprazole increases the gastric pH and interferes with the absorption of the Thyrofit.

Q. Can I take Thyrofit with iron tablets?
No. Thyrofit should not be taken with the iron tablet. The absorption of Thyrofit is decreased when taken together. You should take them with a gap of 4 hours between them.

Q. Can I take Thyrofit with calcium?
No. Thyrofit should not be taken with calcium. The absorption of Thyrofit is decreased when taken with calcium. You should take them with a gap of 4 hours between them.

Q. Can Thyrofit be used in the treatment obesity?
No. Thyrofit should not be used to treat obesity. It can cause weight loss as a side effect but it should not be used for the treatment of obesity as it can cause serious life-threatening side effects if given with other weight reducing medications.

Q. Can Thyrofit be used in the treatment of depression?
No. Thyrofit is not approved for use in depression. But some of the research studies have shown that adding Thyrofit to the antidepressant medication therapy has increased the effectiveness of antidepressant therapy in the patients.

Q. Can Thyrofit help you get pregnant?
Thyrofit treats hypothyroidism (decreased thyroid hormone) and associated complications leading to increases chances of conceiving. Consult your doctor before starting Thyrofit as failure to conceive is not merely due to decreased thyroid hormone but due to several other factors. Always start the medicine consulting with the doctor.

Q. Should I take Thyrofit in morning or evening?
It is preferred to take Thyrofit in morning on empty stomach. Research has shown that even if it is given in the evening, it shows the same effects as compared to morning. It is not practised because of ensuring an empty stomach by the patient.

Q. Is it safe to take Thyrofit if I have a cardiac disease?
Yes. Thyrofit can be used but at a lower dose or given on an alternate day. There are high chances of side effects in a person with the cardiac disease like an increase in heart rate, cardiac wall thickness, and cardiac contractility and it may precipitate angina or irregular heart rhythms. Inform your doctor if you have heart disease. You may adjust the dose.

Q. What are the serious side effects of Thyrofit?
The serious side effects of Thyrofit are usually due to excessive doses, so symptoms are similar to hyperthyroidism. It may cause diarrhoea, vomiting, weight loss with increased appetite, palpitations, angina, insomnia and restlessness. Inform your doctor if you have these symptoms.

Q. Can I take antacids with Thyrofit?
No. Thyrofit should not be taken with an antacid. The absorption of Thyrofit is decreased when taken together. You should take them with a gap of 4 hours between them.

Q. When should I get thyroid function test after starting Thyrofit?
Thyroid function test should be measured three months after starting treatment or change in dose.

Q. Can Thyrofit be taken along with MAO inhibitor?
Yes. Thyrofit can be taken with MAO inhibitors. Consult your doctor before starting these medications.