Plug MF 500 mg/250 mg Tablet 
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NOTICE: unsafe with : Alcohol
COMPOSITION:
Tranexamic Acid (500mg)
Mefenamic Acid (250mg)
Therapeutic Uses:
blood related
pain analgesics
CAUTION
Taking Mefenamic acid with alcohol increases the risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Plug MF 500 mg/250 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Plug MF 500 mg/250 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Plug MF 500 mg/250 mg Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
CAUTION
Plug MF 500 mg/250 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Plug MF 500 mg/250 mg Tablet may be needed. Please consult your doctor.Use of Plug MF 500 mg/250 mg Tablet is not recommended in patients with severe kidney disease.
Plug MF 500 mg/250 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Plug MF 500 mg/250 mg Tablet may not be needed in these patients. Please consult your doctor.
Uses of Tranexamic Acid
Tranexamic Acid is used in the treatment of bleedingIt is used to prevent or reduce bleeding for short period of time in conditions like heavy periods, dysfunctional uterine bleeding, nosebleed, tooth removal, after prostate surgery or after bladder surgery.
How to use Tranexamic Acid
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Plug MF 500 mg/250 mg Tablet is to be taken with food.
How Plug MF 500 mg/250 mg Tablet works
Tranexamic Acid prevents the breakdown of clots and stops bleeding.
Common Nausea, Vomiting, Diarrhoea.
Expert advice for Tranexamic Acid
Do not take tranexamic acid:
before the start of menstruation.
If you are a woman >45 years of ageÂ
If you are allergic to tranexamic acid or any of the ingredients of this medicine
Do not continue tranexamic acid and consult your doctor If you experience skin rashes or other serious symptoms like swelling of face, lips and throat causing breathlessness or difficulty swallowing, as this may denote allergy.Â
Consult your  doctor if menstrual bleeding is not reduced after three menstrual cycles.
To be sure this medication is not causing harmful effects, your vision may need to be tested while you are using tranexamic acid. Follow your doctor's instructions.
Q. What is Tranexamic Acid?
Tranexamic Acid belongs to a group of medicines called anti-fibrinolytics, used to control bleeding. When you bleed, your body form clots to stop the bleeding. In some people these clots break down causing too much bleeding. Tranexamic Acid stops these clots from dissolving, hence reduces bleeding.
Q. Is Tranexamic Acid an over the counter product?
No, Tranexamic Acid is not an over the counter product. it is available as a prescription medicine only.
Q. How long can I take Tranexamic Acid?
It is advisable to take Tranexamic Acid, only for a duration as advised by your doctor.
Q. Does Tranexamic Acid stop menstruation (periods)?
Tranexamic Acid helps to reduce excessive bleeding during a heavy menstrual cycle in women with regular cycles (25-31 days) with not more than 3 days individual variability in cycle duration.
Q. Does Tranexamic Acid affect ovulation?
No, Tranexamic Acid is not known to affect ovulation.
Q. Is Tranexamic Acid safe?
Yes, Tranexamic Acid is safe if used for prescribed duration in prescribed doses as advised by your doctor.
Q. Is Tranexamic Acid an anticoagulant?
No, Tranexamic Acid is not an anticoagulant. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid an non-steroidal antiinflammatory drug (NSAID) or a pain killer?
No, Tranexamic Acid is not a non-steroidal antiinflammatory drug (NSAID) or a pain killer.
Q. Is Tranexamic Acid a hormone?
No, Tranexamic Acid is not a hormone. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid a contraceptive?
No, Tranexamic Acid is not a contraceptive. It belongs to a group of medicines called anti-fibrinolytics
Q. Is Tranexamic Acid a blood thinner?
No, Tranexamic Acid is not a blood thinner. It belongs to a group of medicines called anti-fibrinolytics.
Q. Is Tranexamic Acid a steroid?
No, Tranexamic Acid is not a steroid. It belongs to a group of medicines called anti-fibrinolytics.
Q. Does Tranexamic Acid help in relieving cramps (period pain)?
No, Tranexamic Acid does not help in relieving menstrual cramps (period pain).
Q. Does Tranexamic Acid increases your blood pressure?
There are no reports of Tranexamic Acid causing an increase in blood pressure. Please consult your doctor in case you experience this symptom while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid cause weight gain?
Weight gain has not been reported as a side effect of Tranexamic Acid. Please consult your doctor if you experience excessive weight gain while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid affect fertility?
No, Tranexamic Acid is not known to affect fertility. Please talk to your doctor if you are planning to become pregnant and you are taking Tranexamic Acid.
Q. Does Tranexamic Acid make you tired?
Tiredness has not been reported as a side effect of Tranexamic Acid. Please talk to your doctor in case you experience excessive tiredness while you are taking Tranexamic Acid.
Q. Does Tranexamic Acid prolonged periods?
No, Tranexamic Acid is not known to prolong periods. Please consult your doctor in case you experience this side effect while you are taking Tranexamic Acid.
Q. Can I take Tranexamic Acid with an intrauterine device (IUD) like copper-T?
Tranexamic Acid has been used to treat heavy or prolonged bleeding when an intrauterine device (IUD) like copper-T was in place but the safety of using Tranexamic Acid in this situation has not been established. Please consult your doctor before using Tranexamic Acid while you have an intrauterine device like copper-T in place.
Q. Can I take Tranexamic Acid with ibuprofen?
Tranexamic Acid can be taken with ibuprofen as there are no interactions reported between the two medicines. However, interactions between the two can occur. Please talk to your doctor if you have to take the two medicines together.
Q. Can I take Tranexamic Acid with the oral contraceptives (pills)?
There have been reports suggesting that either Tranexamic Acid or oral contraceptives (pills) containing ethinylestradiol can increase the toxicity of the other by increasing the risk of clot formation in your blood vessels leading to complications like a heart attack. Please consult your doctor in case you are taking these medicines together.
Q. Can I take Tranexamic Acid with amoxicillin?
No interactions have been reported between Tranexamic Acid and amoxicillin. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with a combination of paracetamol and codeine?
No interactions have been clinically observed while taking Tranexamic Acid and a combination of paracetamol with codeine. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with oral contraceptives containing only progesterone like mini pill and medroxyprogesterone acetate?
Tranexamic Acid can be taken with oral contraceptives containing only prgesterone as there are no drug interactions reported. However this does not role out the possibilty of interactions existing. Please talk to your doctor before taking Tranexamic Acid if you are already taking a progesterone containing oral contraceptive like mini-pill and medroxyprogesterone acetate.
Q. Can I take Tranexamic Acid with paracetamol?
No interactions have been reported between Tranexamic Acid and paracetamol. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with mefenamic acid?
No interactions have been reported between Tranexamic Acid and mefenamic acid. However, interactions can occur. Please talk to your doctor before taking the two medicines together.
Q. Can I take Tranexamic Acid with diclofenac?
No drug interaction of Tranexamic Acid with diclofenac has been clinically observed. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Uses of Mefenamic Acid
Mefenamic Acid is used in fever, arthralgia, muscle pain, osteoarthritis, rheumatoid arthritis, post operative pain and pain during menstruation.
How to use Mefenamic Acid
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Plug MF 500 mg/250 mg Tablet is to be taken with food.
How Plug MF 500 mg/250 mg Tablet works
Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Common Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.
Expert advice for Mefenamic Acid
It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Mefenamic Acid can raise your risk of blood clots, heart attack, or a stroke. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Q. Is mefenamic acid an antibiotic/ contain codeine?
No. Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat mild to moderate pain conditions and fever. It not an antibiotic and does not contain codeine
Q. Is Mefenamic Acid a painkiller?
Yes. Mefenamic Acid is mild to moderate painkiller drug
Q. Is Mefenamic Acid safe?
Mefenamic Acid is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Mefenamic Acid good for toothache/ for back pain/ headache?
Yes, Mefenamic Acid can be used to relieve dental pain, back pain and headache
Q. Does Mefenamic Acid stop periods/ stop bleeding?
Mefenamic Acid is used for relieving pain that happens before or during a menstrual period. It does not stop periods or bleeding. Always consult your doctor regarding its use
Q. Can I take mefenamic acid with naproxen/ paracetamol/ ibuprofen/ metronidazole/ withtramadol/ with tranexamic acid/ with sertraline/ amoxicillin?
Mefenamic acid may interact with the drugs mentioned above. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be require
Q. Does Mefenamic Acid make you drowsy?
Mefenamic Acid has a rare side effect of causing drowsiness. Always consult your doctor, if you experience such side effects.
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