Common Nausea, Vomiting, Headache, Dizziness, Constipation, Weakness.

Expert advice for Ranolaz Tablet ER
Ranolaz prevents new attacks of angina but does not stop an acute attack. Does not affect heart rate, blood pressure at rest or during exercise. Improves HbA1c and blood sugar levels in diabetes patients. Avoid driving or using machinery if you feel dizzy after taking Ranolaz. May produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done 1 to 2 weeks after starting Ranolaz. Notify your doctor if you are taking any other medications along with Ranolaz

Q. What is Ranolaz extended-release(ER) tablet?
Ranolaz extended release (ER) means the pill is formulated in such a manner that the drug is released slowly over time and blood levels of a drug are more consistent. This has the advantage of taking fewer pills and also with a lesser gastrointestinal side effect.

Q. Do Ranolaz and trimetazidine act in the same way?
No. Both Ranolaz and trimetazidine are used for the treatment of angina but they work by a different mechanism. Ranolaz works by blocking late sodium current channel during ischemia and thereby lessens the intracellular sodium and calcium overload. This relaxes heart muscles and decreases the oxygen requirement. This helps to prevent angina. Trimetazidine works by improves glucose utilisation of heart cells through inhibition of fatty acid metabolism.

Q. What is the effect of Ranolaz in patients with coronary artery disease?
The researcher has studied Ranolaz in patients with non-ST-elevation coronary artery disease. It did not reduce the risk of death or recurrent heart attacks in patients, but it improves angina symptoms. It is approved for use in angina.

Q. Can I use rivaroxaban with Ranolaz?
Yes. Combining these medications can increase the blood levels of rivaroxaban and increase the risk of serious bleeding complications. You may need a dose adjustment. If you have kidney disease, you should inform your doctor before using rivaroxaban together with Ranolaz.

Q. Can I take Ranolaz for type 2 diabetes?
No. Ranolaz is not approved for treatment of type 2 diabetes. Study have demonstrated its ability to decrease HbA1c (glycosylated haemoglobin) in patients with or without diabetes. This property may be useful in the treatment of patients having diabetes mellitus and angina.

Q. Can I take Ranolaz with quetiapine?
No. Using Quetiapine with Ranolazine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.

Q. Is Ranolaz good for the heart?
Ranolaz is used in a disease of the heart known as angina. It has been shown to improve exercise-induced chest pain and severity of angina.

Q. Are any alternatives to Ranolaz?
Yes, there are alternative to Ranolaz e.g.Ivabradine, nicorandil and trimetazidine for effective control of anginal symptoms.

Q. Can I take Ranolaz with atorvastatin?
Yes. Ranolaz may significantly increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and the breakdown of skeletal muscle tissue. It can be used with atorvastatin but with dose limitation (atorvastatin) and appropriate clinical monitoring. In some cases, this can cause kidney damage and even death.

Q. Can I use Ranolaz for the treatment of atrial fibrillation?
No. Ranolaz is not approved for treatment of atrial fibrillation (AF). The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.

Q. Is Ranolaz a beta blocker?
No, Ranolaz is not a beta blocker. It is used in the treatment of angina.

Q. Can I take Ranolaz with haloperidol?
No. Ranolaz should not be used with haloperidol. It may increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.

Q. Is Ranolaz effective in arrhythmia?
No. Ranolaz is not approved for use in any of arrhythmia. The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.

Q. What are the contraindications to Ranolaz?
Ranolaz is contraindicated in patients with liver damage (cirrhosis). It should not be given with medicine like ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, saquinavir, carbamazepine, phenobarbital, phenytoin, rifampin.

Q. Can I use Ranolaz for the treatment of diastolic heart failure?
No. Ranolaz is not used in the treatment of diastolic heart failure. It is used in the treatment of angina.