Common Application site reactions (burning, irritation, itching and redness), Skin infection.

Expert advice for Topgraf Ointment
Wash your hands before applying Topgraf. Apply a thin layer to the areas of skin affected by atopic dermatitis (eczema). Make sure your skin affected by atopic dermatitis (eczema) is completely dry especially after bath or shower. Limit sun exposure during treatment even when the medicine is not applied on the skin. Do not cover the skin being treated with bandages or dressings. You can wear normal clothing. Avoid getting Topgraf in the eyes or mouth. If the Topgraf gets on any of these areas, it should be thoroughly wiped off and/or rinsed off with water. Stop Topgraf when the signs and symptoms of atopic dermatitis (eczema) such as itching, rash, and redness go away or consult your doctor. Not recommended to be used for more than 6 weeks and if needed, treatment may be repeated with breaks in-between. Can’t be used if your immune system is weak (for example, if you have cancer or are taking steroids for a long time). Inform your doctor if you have any infection on your skin including chicken pox or herpes. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Many people see an improvement in their skin in as early as one week. Not recommended in children aged below 2 years.

Q. Is tacrolimus a steroid?
Tacrolimus is an immunosuppressant drug. It is not a steroid drug

Q. Is tacrolimus nephrotoxic or cytotoxic?
Tacrolimus may cause destruction of certain types of cells (cytotoxic) and may impair kidney function (nephrotoxic). Patients should follow the advice of the doctor regarding its use.