Side Effects:

Common Nystagmus (involuntary eye movement), Double vision, Sleepiness, Anemia, Peripheral neuropathy (tingling and numbness of feet and hand), Gingival hyperplasia, Increased hair growth, Osteoporosis.

Expert advice for Protoin Tablet
Protoin should be taken at the same time every day to maintain consistent levels in your body. Do not stop using Protoin without talking to your doctor, even if you feel better. It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery. Avoid consuming alcohol when taking the Protoin, as it may cause excessive sleepiness or drowsiness. It may increase blood sugar levels.Inform your doctor if you are taking any medicines to treat diabetes. Do not start any medicine including herbal or ayurvedic without telling your doctor. As it may significantly change the Protoin levels. Inform your doctor if you have ever been diagnosed with kidney or liver problems. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Frequently Asked Questions

Q. How does Protoin work?
Protoin is used to control seizures (fits) in epilepsy patients and it works by suppressing the abnormal and excessive activity of the nerve cells in the brain.

Q. Does Protoin cause gingival hyperplasia?
Protoin is known to cause gingival hyperplasia (enlarged gums). To avoid this, you must maintain a good dental hygiene (taking proper care of your teeth and gums). Please consult your doctor if you have enlarged gums after taking Protoin.

Q. Does Protoin cause osteomalacia?
Osteomalacia (softening of the bones) has been associated with long-term (>10 years) use of Protoin by patients with chronic epilepsy. There have been reports of bone disorders including osteopenia (reduced protein and mineral content of bone tissue) and osteoporosis (thinning of the bone) and fractures with Protoin. Please consult your doctor for further information.

Q. Can I take Protoin with aspirin?
Protoin can decrease the levels of aspirin by increasing its metabolism (breakdown) and hence decrease its effect. Please consult your doctor before taking the two medicines together.

Q. Can I take Protoin with ibuprofen?
Protoin can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Can I take Protoin with paracetamol?
Protoin decreases the level of paracetamol by increasing its metabolism (breakdown). Increased metabolism of paracetamol can increase the levels of substances that can cause liver damage. Please consult your doctor before taking the two medicines together.

Q. Is Protoin a narcotic?
Protoin is not a narcotic substance. Protoin belongs to a group of medicines known as anti-epileptic medicines, these medicines are used to treat epilepsy.

Q. Is Protoin a controlled substance?
Protoin is not a controlled substance under the Controlled Substance Act (CSA). A controlled substance is generally a drug or chemical whose manufacture, possession or use is regulated by a government.

Q. Is Protoin dialyzable?
Protoin is not dialyzable by a conventional hemodialysis machine but can be dialyzed by a high permeability type of hemodialysis. To know more about the different types of dialysis and dialysability of Protoin, please consult your doctor.

Q. Is Protoin teratogenic (cause birth defects)?
Protoin is teratogenic. Based on human experience, Protoin is suggested to cause congenital malformations (birth defects) when given during pregnancy. It can cause defects of the heart, brain, fingers and can decrease the growth of the unborn baby.

Q. Is Protoin a cytochrome P450 (CYP450) inducer?
Cytochrome P450 (CYP450) is an enzyme which causes metabolism (breakdown) of many drugs. Protoin is a CYP450 enzyme inducer (increases the working of CYP450) causing increased breakdown of some medicines given along with Protoin (known as drug-drug interactions). Please consult your doctor before taking any medicines along with Protoin as it may affect the metabolism of the medicines which are metabolized by CYP450 for example Vitamin D.

Q. Is Protoin basic or acidic?
Protoin is a weakly acidic drug.

Q. Is Protoin addictive?
Protoin has not been reported to have any addictive potential and it does not show any symptoms of dependence. However, it should be taken for the duration as advised by your doctor.

Q. Does Protoin get you high?
Protoin does not give you a high.

Q. Does Protoin cause hyponatremia?
Protoin does not cause hyponatremia (low sodium levels). However, Protoin is known to cause hypernatremia (high serum sodium level >145 mmol/L).

Q. Does Protoin cause QT prolongation?
Protoin is not known to cause QT prolongation (abnormal heart rhythm). However, it can rarely cause abnormal heart rhythms. Please talk to your doctor if you have any abnormal heart rhythm (beats) while taking Protoin.

Q. Does Protoin affect thyroid?
Thyroid function may get affected while you are taking Protoin, especially in children. Thyroid function should be monitored while taking Protoin. Please consult your doctor if you have hypothyroidism or a history of hypothyroidism.

Q. Does Protoin cause weight gain?
Protoin has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Protoin. Please consult your doctor if you experience weight gain after taking Protoin.

Q. Does Protoin make you sleepy (sedation)?
Protoin can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Protoin, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.

Q. Does Protoin affect birth control?
Protoin does affect birth control. Protoin can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.