Zucox Plus 450 mg/300 mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd

prescription required

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In-stock 10 tablets in 1 strip
62.41

NOTICE: unsafe with : Alcohol

USED FOR:
Tuberculosis (TB)

COMPOSITION:
Rifampicin (450mg) + Isoniazid (300mg)

Therapeutic Uses:
anti infectives

Related Warnings
CAUTION
Alcohol
CAUTION

Zucox Plus 450 mg/300 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

WEIGH RISKS VS BENEFITS
Pregnancy
WEIGH RISKS VS BENEFITS

Zucox Plus 450 mg/300 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

SAFE
Lactation
SAFE

Zucox Plus 450 mg/300 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

Driving

Do not drive unless you are feeling well.Zucox Plus 450 mg/300 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.

CAUTION
Kidney
CAUTION

Zucox Plus 450 mg/300 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zucox Plus 450 mg/300 mg Tablet may be needed. Please consult your doctor.

CAUTION
Liver
CAUTION

Zucox Plus 450 mg/300 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zucox Plus 450 mg/300 mg Tablet may be needed. Please consult your doctor.Use of Zucox Plus 450 mg/300 mg Tablet is not recommended in patients with severe liver disease.

Rifampicin+Isoniazid   450mg + 300mg

Uses of Zucox Plus Tablet
Zucox Plus 450 mg/300 mg Tablet is used in the treatment of tuberculosis.

How to use Zucox Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zucox Plus 450 mg/300 mg Tablet is to be taken empty stomach.Avoid Zucox Plus 450 mg/300 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Zucox Plus 450 mg/300 mg Tablet works
Zucox Plus 450 mg/300 mg Tablet is a combination of two antibiotics: Rifampicin and isoniazid which treat tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Isoniazid prevents the TB-causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

Side Effects:

Common Nausea, Vomiting, Rash, Fever, Sweating, Dark colored urine, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice, Incresed sputum production.