Wokex 4 Plus Tablet 
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NOTICE: unsafe with : Alcohol
USED FOR:
Tuberculosis (TB)
COMPOSITION:
Rifampicin (NA) + Isoniazid (NA) + Ethambutol (NA) + Pyrazinamide (NA) + Vitamin B6 (Pyridoxine) (NA)
Therapeutic Uses:
anti infectives
CAUTION
Wokex 4 Plus Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
Wokex 4 Plus Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Wokex 4 Plus Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Do not drive unless you are feeling well.Wokex 4 Plus Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Wokex 4 Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Wokex 4 Plus Tablet may not be needed in these patients. Please consult your doctor.
Wokex 4 Plus Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Wokex 4 Plus Tablet may not be needed in these patients. Please consult your doctor.
Uses of Wokex 4 Plus Tablet
Wokex 4 Plus Tablet is used in the treatment of tuberculosis.
How to use Wokex 4 Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Wokex 4 Plus Tablet is to be taken empty stomach.
How Wokex 4 Plus Tablet works
Wokex 4 Plus Tablet is a combination of five medicines: Rifampicin, isoniazid, ethambutol, pyrazinamide and vitamin B6 (pyridoxine) which treat tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents the these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide, on the other hand work by slowing the growth of these bacteria. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.
Common Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice, Increased uric acid level in blood, Visual impairment.
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