Ratifed 500 mg/2.5 mg Tablet may cause excessive drowsiness and calmness with alcohol.

Ratifed 500 mg/2.5 mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Ratifed 500 mg/2.5 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Ratifed 500 mg/2.5 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.Caution is advised when driving or operating machinery.

Ratifed 500 mg/2.5 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ratifed 500 mg/2.5 mg Tablet may be needed. Please consult your doctor.Use of Ratifed 500 mg/2.5 mg Tablet is not recommended in patients with severe kidney disease.

Ratifed 500 mg/2.5 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Ratifed 500 mg/2.5 mg Tablet may be needed. Please consult your doctor.