Side Effects:

Common Nausea, Headache, Abdominal pain, Constipation, Flatulence, Diarrhoea.

Expert advice for Rebzole Tablet
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Rebzole can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.  Inform your doctor if you are suffering from osteoporosis as Rebzole can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate. Rebzole is a well-tolerated medicine and provides relief for a long time. It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them. Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Frequently Asked Questions

Q. Is Rebzole an over the counter product?
No, Rebzole is not an over the counter product, it is available when prescribed by a doctor.

Q. Is Rebzole an antacid?
Rebzole is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.

Q. Does Rebzole cause osteoporosis (thinning of bones)?
Yes, long term use of Rebzole can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with Rebzole?
Rebzole can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Rebzole takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Rebzole as antacids can increase the pH of the stomach and decrease the action of Rebzole which requires a lower pH for its action.

Q. Does Rebzole have addictive potential?
No, Rebzole has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.

Q. Is Rebzole safe?
Yes, Rebzole is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Rebzole cause hair loss?
No, hair loss has not been reported as a side effect of Rebzole. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.

Q. Does Rebzole cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Rebzole. Although it would be mild to moderate in nature and transient.

Q. Does Rebzole cause tinnitus (ringing in the ears)?
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Rebzole. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.

Q. Does Rebzole cause weight gain?
Weight gain has been reported as a rare side effect of Rebzole. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.

Q. Does Rebzole expire?
Yes, like any other medicine, Rebzole also expires. Always check the expiry date on the pack of the medicine before using it.

Q. Does Rebzole cause constipation?
Constipation is a common side effect seen in patients using Rebzole. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.

Q. Does Rebzole cause high blood pressure?
Rebzole is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Rebzole includes nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Rebzole cause headache?
Headache is reported as one of the common side effects of Rebzole. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Rebzole.

Q. Can I take Rebzole with ranitidine?
Yes, Rebzole can be taken with ranitidine. As Rebzole show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.

Q. Can I take Rebzole with ibuprofen?
Rebzole can be taken with ibuprofen. Rebzole is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. Can I take Rebzole with paracetamol?
Rebzole can be taken with paracetamol. Rebzole is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. How is Rebzole metabolized?
Rebzole is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Rebzole for a long time and a better suppression of stomach acid.

Q. Can Rebzole be used for the treatment of throat infection?
No, Rebzole is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.

Q. Why is Rebzole used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Rebzole.

Q. Does Rebzole play any role in treating ulcerative colitis?
Rebzole does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.

Q. Can Rebzole be used for reflux esophagitis?
Yes, Rebzole is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Rebzole decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.

Q. Is Rebzole being used for treating weight loss?
No, Rebzole is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

Q. Is there any role of Rebzole in treating hiatus hernia?
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Rebzole does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.

Q. Can I take Rebzole with vitamin D?
Yes, vitamin D can be taken with Rebzole. Vitamin D is generally advised to be taken as a supplement with Rebzole as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.

Q. How is Rebzole useful in the treatment of H. pylori?
Rebzole is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.

Q. Can I take Rebzole with domperidone?
Rebzole can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Can long term use of Rebzole cause magnesium deficiency?
Long-term use of Rebzole can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.