Side Effects:

Common Fatigue, Drowsiness, Headache, Constipation, Diarrhoea, Muscle pain.

Expert advice for Retin Tablet
Retin is a well tolerated and safe medicine with a very low incidence of side effects. Take Retin before going to bed if you are taking this medicine once a day as it is very effective in controlling stomach acid released in the midnight. If you are also taking an antacid, take it two hours before or after taking Retin. Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion. Inform your doctor if you do not feel better after taking Retin for two weeks or 14 days as you may be suffering from some other problems. Inform your doctor if you have ever been diagnosed with kidney or liver disease. Dose of your medicine may need to be adjusted.

Frequently Asked Questions

Q. Is Retin an over the counter (OTC) drug?
No, Retin is not an over-the-counter product. It is a prescription medicine and is available only when prescribed by a physician.

Q. Can I take Retin with azithromycin?
Yes, Retin can be taken with azithromycin. Retin may be given to lower the acid secretion caused by gastritis or stomach irritation caused by azithromycin. No drug-drug interactions or any additional harmful effects have been seen when they are used together compared to when they are used alone.

Q. Can the use of Retin cause constipation?
Yes, the use of Retin can cause constipation. It is one of the common side effect seen with Retin. Taking high fiber diet and plenty of fluids can help in relieving constipation and can also help in decreasing acidity.

Q. Can I take Retin with prednisone?
Yes, Retin can be taken with prednisone. No drug-drug interactions or any change in side effect profile have been when these are used together compared to when each drug is used alone.

Q. Can I take Retin with metoprolol?
Yes, Retin can be taken with metoprolol. No drug-drug interactions or any change in side effect profile have been reported compared to when they are used alone.

Q. Is Retin an antacid?
No, Retin is not an antacid. It belongs to the class of H2 blockers (antihistamines) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.

Q. Can I take Retin for the treatment of allergies or hives (urticaria)?
Retin can help in decreasing the redness of the allergies or hives (urticaria) when used along with antihistaminics like cetirizine by narrowing the blood vessels. However, this is not an approved use of Retin and should be used only when advised by a doctor.

Q. Does Retin expire?
Yes, Retin does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Retin after the expiry date.

Q. Can I take Retin with tramadol?
Yes, Retin can be taken with the tramadol. Retin may be given to lower the acid secretion caused by gastritis or stomach irritation caused by tramadol. No drug-drug interactions or any change in side effect profile has been reported compared to when they are used alone.

Q. Is Retin an antihistaminic drug?
Yes, Retin is an antihistaminic drug. It acts on histamine receptors in the stomach and blocks the action of a chemical messenger histamine (causes acid secretion in stomach) and hence decreases the acid production in the stomach.

Q. Is Retin safe?
Yes, Retin is safe if used at prescribed doses for the prescribed duration as advised by the doctor. However, there are some very common side effects that you can experience at the doses advised like nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Can I take Retin with doxycycline?
Yes, Retin can be taken with doxycycline. Retin may be given to lower the acid secretion caused by gastritis or stomach irritation caused by doxycycline. No drug-drug interactions or any change in side effect profile has been reported compared to when they are used alone.

Q. Does Retin interfere with H. pylori test results?
A significant number of patients infected with Helicobacter pylori can have negative test results if they are using Retin as it interferes with the urea breath test, which is done to identify H. Pylori infection.

Q. Can I take Retin with Rabeprazole?
Yes, Retin and Rabeprazole can be taken together. As Rabeprazole show its effect after some days, Retin can be taken along with for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.

Q. Can I take Retin with sertraline?
Yes, Retin can be taken with sertraline. No drug-drug interactions or any change in side effect profile has been reported compared to the effect of the individual drug when used alone.

Q. Does Retin cause glaucoma?
Retin itself does not cause glaucoma. However, there are some rare reports that Retin can increase the intraocular pressure in patients who have glaucoma. Inform your doctor in case you have glaucoma or high intraocular pressure before taking this medicine.

Q. Can I take Retin with steroids?
Yes, Retin can be taken with steroids. No drug-drug interactions or any change in side effect profile has been reported compared to the effect of the individual drug when used alone.

Q. Can I take Retin with famotidine?
Both Retin and famotidine lower gastric acid secretion by blocking the H2 (histamine) receptor in the stomach. It is not advisable to take them together as they have a similar action and use and when used together, there could be an increased risk of side effects.

Q. Can Retin be used to treat gastritis?
Yes, Retin can be used for the short-term treatment of gastritis. It helps by decreasing the amount of acid released into the stomach and relieving stomach pain and acid reflux.

Q. Can I take Retin with vitamin B?
Yes, Retin can be taken with vitamin B. No drug-drug interactions have been reported between this medicine and vitamin B.

Q. Can a patient of hepatitis B take Retin?
Caution should be exercised when Retin is given to patients with a liver disease like hepatitis B as it is metabolized in the liver. Retin can be taken by a patient of hepatitis B if it is really essential and advised by a doctor. Very rare reports of hepatitis with or without jaundice have been documented in patients taking Retin.

Q. Why Retin is given along with vitamin B12?
Long term use of Retin can cause vitamin B12 deficiency as it decreases the acid secretion in the stomach which is required for the absorption of Vitamin B12. To prevent this deficiency, vitamin B12 may be advised by your doctor along with this medicine.

Q. Can I take Retin with vitamin C?
Yes, you can take Retin with vitamin C. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.

Q. Can a patient with hepatitis C take Retin?
Yes, a patient of hepatitis C can take Retin, however, this should be taken under medical supervision. Retin belongs to the group of drugs called H2 blockers which have been seen to increase the risk of hepatic encephalopathy in hepatitis C patients. So, this group of medicines should be used with caution in patients with underlying liver disease.

Q. Can Retin be used with vitamin D?
Yes, vitamin D can be taken with Retin. It is generally advised to be taken as a supplement as the long-term use of Retin decreases the absorption of calcium and cause calcium deficiency leading to osteoporosis (thinning of bones) and increasing the risk of bone fractures like hip, wrist and spine fractures.

Q. Can the use of Retin cause gastroparesis (partial paralysis of the stomach)?
No, the use of Retin is not known to cause gastroparesis (partial paralysis of the stomach), however in case you experience signs and symptoms of gastroparesis like persistent nausea, vomiting (especially of undigested food) and abdominal pain or a feeling of fullness after eating even small amount of food, consult your doctor as it may be due to some condition that needs attention.

Q. Can the use of Retin make you feel high?
No, Retin does not make you feel high. However, use of Retin can cause mental confusion, irritability, depression, though very rarely. These undesirable side effects occur usually in elderly or severely ill or kidney disease patients.

Q. Can the use of Retin cause high blood pressure?
Retin is not reported to cause high blood pressure. In case you experience high blood pressure,inform your doctor as it may need attention. Common side effects seen with Retin include nausea, abdominal pain, constipation, and diarrhea.

Q. Can I use Retin for treating warts?
No, Retin is not used for treating warts as it is not approved for this disease condition. However, some research studies have shown that Retin can improve the effect of medicines used for the treatment of this condition. Warts are a viral condition in which the patient has small, rough, and hard growths like raised bumps on the skin. Avoid self-medication and talk to a doctor for the right treatment of warts as it may bleed or get infected or spread to other body parts if not treated properly.

Q. Can I use Retin for stomach pain?
Stomach pain can be due to many reasons and Retin can help in this condition if the stomach pain is due to an underlying acid-peptic disorder.

Q. Can the use of Retin cause headache?
Headache is reported as one of the common side effects of Retin. Inform your doctor in case you experience headache for a prolonged duration while taking Retin.

Q. Why does Retin cause pneumonia?
Patients using Retin are two times more prone to develop pneumonia (infection of the lung) than the normal patients. Retin by means of its acid suppressing ability may allow growth of bacteria in the gut which can move to the respiratory tract (lungs) following breathing. So inform your doctor if you have or a history of lung disease as your dosage may need to be adjusted.

Q. What is the role of Retin in critically ill patients?
Retin may be used in critically ill patients to decrease stomach acid secretion and lower the risk of acid aspiration into the lungs. It also helps in decreasing stomach ulcers and gastrointestinal bleeding in these patients.

Q. What foods should be avoided when you are taking Retin?
You should preferably avoid foods that cause acidity and heartburn as they would aggravate your disease condition, for example: fried foods, prepared in butter or oil, fat rich foods, tomato-based foods and juices, caffeinated drinks like cola, tea, drinks from citrus fruits like lemon water or orange juice and alcohol-containing drinks.

Q. Can Retin be used for reflux esophagitis?
Yes, Retin is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Retin decreases the production of acid in the stomach and this can help to heal the inflamed and eroded esophagus. The efficacy is better when it is given in combination with a prokinetic agent like domperidone.

Q. Can I take Retin with paracetamol?
Yes, you can take Retin with paracetamol. Retin is used to prevent paracetamol (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.

Q. Why is Retin given with cancer drugs?
Retin may be used for multiple reasons in cancer patients. It can lower stomach acid volume in patients undergoing chemotherapy to prevent aspiration and lower the risk of stomach ulceration and bleeding. According to some studies, Retin can potentiate white blood cell against cancer cells and can be helpful in the treatment of cancer.

Q. Does Retin treat irritable bowel syndrome (IBS)?
Retin is not routinely used for the treatment of irritable bowel syndrome (IBS). It is given if there is associated dyspepsia or increased stomach acid secretion. IBS is managed with a combination of antispasmodics (to relieve stomach pain), laxatives (to relieve constipation), and anti motility drugs (to relieve diarrhea).

Q. Is Retin used to treat nausea?
Retin is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers and can help in providing relief in nausea that may happen due to acid reflux. It is not used to treat nausea due to any other cause. Rather, nausea is one of the most common side effects of Retin.

Q. What is the benefit of taking Retin with pantoprazole?
Both Retin and pantoprazole lower gastric acid secretion, however, they work by different mechanisms. If you have been advised to take pantoprazole, you can also take Retin initially for rapid relief of heartburn and acid reflux as pantoprazole may take a few days to show its effect and provide relief.

Q. Can I take Retin with pain killers?
Yes, Retin can be taken with painkillers. Retin can help to prevent painkillers induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. Moreover, there are no clinically significant interactions of Retin with painkillers.

Q. What are the serious side effects associated with the use of Retin?
Some serious side effects associated with the use of Retin are bone marrow hypoplasia (decreased formation of blood cell components), anaphylactic shock (severe allergic reactions) sinus bradycardia (lowering of heart rate) and acute pancreatitis (inflammation of the pancreas).

Q. Why does Retin cause diarrhea?
Use of Retin lowers the natural stomach acid which normally helps to kill bacteria. So, use of Retin leads to overgrowth of the harmful bacteria like clostridium difficile which can cause diarrhea. This is known as clostridium difficile–associated diarrhea (CDAD). Inform your doctor if you have loose stools many times in a day and for many days with stomach cramps and fever.

Q. Is Retin effective?
Retin would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. In case you do not find any change in your disease condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.

Q. Is Retin useful in the prevention of painkiller (NSAID) induced gastric ulcers?
Yes, Retin is useful for the prevention of painkiller (non-steroidal anti-inflammatory drug - NSAID) induced gastric ulcers. These may cause dull pain in the stomach, sudden weight loss, loss of appetite, nausea, vomiting or bloating. Avoid stress and spicy foods as they can make your symptoms worse.

Q. Can I smoke while taking Retin?
It is better to avoid cigarette smoking when you are taking Retin. As studies have shown that the effectiveness of Retin is lower in smokers compared to non-smokers. Moreover, smoking may add to gastric problems leading to more production of gastric acid.

Q. Does Retin increase uric acid levels and cause gout-like symptoms?
Retin can increase blood uric acid levels and cause gout-like symptoms like pain, redness, and inflammation of joints and cause difficulty in movement of joints. Regular monitoring of uric acid levels may be advised if you are taking this medicine for a long term.

Q. Can I take Retin with warfarin?
Yes, Retin can be taken with warfarin. However, they should be used with caution as there could be an increase in warfarin levels which can increase the risk of bleeding from your gums, nose, skin (unusual bruising), or gut (dark stools). Stop taking the medicine and inform your doctor if you have any of these signs or symptoms.

Q. Can I take Retin with gabapentin?
Yes, Retin can be taken with gabapentin. There are no reported drug interactions or harmful effects when they are used together.

Q. Can I take Retin with cetirizine?
Yes, Retin can be taken with cetirizine. There are no reported drug interactions or harmful effects when they are used together.

Q. Is Retin a proton pump inhibitor (PPI)?
No, Retin is not a proton pump inhibitor (PPI) as it has no known inhibitory effect on proton pumps in the stomach.

Q. Can the use of Retin cause iron deficiency?
Yes, use of Retin can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Retin but you can maintain good dietary nutrition so that no deficiency occurs.

Q. Is there any known role of Retin before surgery?
Retin is given as a part of pre-anesthetic medication before surgery to decrease the stomach acid secretion so that stomach acid is not aspirated into the lungs during surgery as this may complicate or delay the procedure.

Q. Does Retin cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Retin. Although it would be mild to moderate in nature and it goes away once you stop taking Retin.