Side Effects:

Common Nausea, Headache, Abdominal pain, Constipation, Flatulence, Diarrhoea.

Expert advice for Rebol Tablet
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Rebol can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.  Inform your doctor if you are suffering from osteoporosis as Rebol can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate. Rebol is a well-tolerated medicine and provides relief for a long time. It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them. Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Frequently Asked Questions

Q. Is Rebol an over the counter product?
No, Rebol is not an over the counter product, it is available when prescribed by a doctor.

Q. Is Rebol an antacid?
Rebol is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.

Q. Does Rebol cause osteoporosis (thinning of bones)?
Yes, long term use of Rebol can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with Rebol?
Rebol can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Rebol takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Rebol as antacids can increase the pH of the stomach and decrease the action of Rebol which requires a lower pH for its action.

Q. Does Rebol have addictive potential?
No, Rebol has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.

Q. Is Rebol safe?
Yes, Rebol is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Rebol cause hair loss?
No, hair loss has not been reported as a side effect of Rebol. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.

Q. Does Rebol cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Rebol. Although it would be mild to moderate in nature and transient.

Q. Does Rebol cause tinnitus (ringing in the ears)?
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Rebol. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.

Q. Does Rebol cause weight gain?
Weight gain has been reported as a rare side effect of Rebol. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.

Q. Does Rebol expire?
Yes, like any other medicine, Rebol also expires. Always check the expiry date on the pack of the medicine before using it.

Q. Does Rebol cause constipation?
Constipation is a common side effect seen in patients using Rebol. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.

Q. Does Rebol cause high blood pressure?
Rebol is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Rebol includes nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Rebol cause headache?
Headache is reported as one of the common side effects of Rebol. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Rebol.

Q. Can I take Rebol with ranitidine?
Yes, Rebol can be taken with ranitidine. As Rebol show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.

Q. Can I take Rebol with ibuprofen?
Rebol can be taken with ibuprofen. Rebol is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. Can I take Rebol with paracetamol?
Rebol can be taken with paracetamol. Rebol is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. How is Rebol metabolized?
Rebol is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Rebol for a long time and a better suppression of stomach acid.

Q. Can Rebol be used for the treatment of throat infection?
No, Rebol is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.

Q. Why is Rebol used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Rebol.

Q. Does Rebol play any role in treating ulcerative colitis?
Rebol does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.

Q. Can Rebol be used for reflux esophagitis?
Yes, Rebol is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Rebol decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.

Q. Is Rebol being used for treating weight loss?
No, Rebol is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

Q. Is there any role of Rebol in treating hiatus hernia?
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Rebol does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.

Q. Can I take Rebol with vitamin D?
Yes, vitamin D can be taken with Rebol. Vitamin D is generally advised to be taken as a supplement with Rebol as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.

Q. How is Rebol useful in the treatment of H. pylori?
Rebol is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.

Q. Can I take Rebol with domperidone?
Rebol can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Can long term use of Rebol cause magnesium deficiency?
Long-term use of Rebol can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.