Palonosetron is used in the treatment and prevention of nausea and vomiting.

Palonosetron is an antiemetic (anti-nausea medicine). It inhibits the action of serotonin, a chemical messenger that can trigger nausea and vomiting.

Fatigue, Headache, Flushing (sense of warmth in the face, ears, neck and trunk), Injection site allergic reaction, Constipation

• Take Palonosetron 30 minutes before your food.
• If you vomit within 30 minutes after taking the Palonosetron, take the same amount again. If vomiting continues, check with your doctor.
• If Palonosetron is used for a short duration, for e.g. 6 -10 days, the risk of side-effects is minimal (well-tolerated).
• You can use oral disintegrating film/strip (medicated strip that dissolves when comes in contact with a wet surface) form of the Palonosetron if you are nauseous to swallow a tablet or capsule.
• If you are using Palonosetron in the form of oral disintegrating film/strip:
  
  • Make sure your hands are dry.
  • Immediately place the film/strip on the top of the tongue.
  • The film/strip will dissolve in seconds and you can swallow it with your saliva.
  • You do not need to drink water or other liquids to swallow the film/strip.

Ques. Q. What is Palonosetron HCl?
Palonosetron hydrochloride or Palonosetron is a serotonin (5HT3) antagonist

Ques. Q. How does Palonosetron work?
Palonosetron belongs to a class of antiemetic medications called serotonin (5HT3) antagonists. It binds to special sites called serotonin 5HT3 receptors and blocks the action of serotonin, a naturally released chemical in the body that triggers nausea and vomiting.