Bortezomib is used in the treatment of multiple myeloma and mantle-cell lymphoma.

Bortezomib is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.

Reduced blood platelets, Fatigue, Peripheral neuropathy (tingling and numbness of feet and hand), Psychiatric disturbances, Nausea, Vomiting, Loss of appetite, Fever, Anemia, Diarrhoea, Decreased appetite, Decreased white blood cell count (neutrophils), Constipation

• Before taking bortezomib, consult your doctor if you have any of the following disease conditions: disease of liver, kidney, heart or infections like fever with rash or genital sores, diabetes, low number of red or white blood cells or bleeding problems.
• Drink plenty of fluids every day during your treatment with bortezomib.
• Tell your doctor if you are or planning to become pregnant or are breastfeeding.
• Consult your doctor if you have signs of serious brain infection such as memory loss, trouble in thinking, difficulty with walking or loss of vision.
• Do not drive or operate machinery after taking bortezomib as it may cause tiredness, dizziness, fainting or blurred vision.

Ques. Q. Is Bortezomib a chemotherapy/hormonal drug/ cytotoxic?
Bortezomib is not a hormone. It is a chemotherapy/ cytotoxic drug used in the treatment of cancers including multiple myeloma and mantle cell lymphoma

Ques. Q. How does Bortezomib work?
Bortezomib belongs to the class of drugs called a proteasome inhibitor. It acts by blocking the action of proteasome, and affects the growth of cancerous (actively growing) cells

Ques. Q. Is Bortezomib FDA approved?
Yes, Bortezomib is approved by FDA

Ques. Q. Is Bortezomib dialyzable?
Yes, Bortezomib is dialyzable

Ques. Q. Is Bortezomib toxic?
Bortezomib can cause toxic effects if not given in appropriate dose although not everybody gets them

Ques. Q. Does Bortezomib cause constipation?
Bortezomib may cause side effects such as constipation.